Innovation

Research and development are essential to all industries but even more so in the pharma and biotech sectors where the rapid flow of new innovations compels players across the value chain to rise to the challenge. Kymos was founded by expert researchers and as a CRO we remain committed to constantly upgrading to the latest cutting-edge technology for analytical development, characterization, and quality control of drugs. In fact, we have mastered disruptive, emerging technologies long before our competitors: our 10-year-old biologics laboratories, our work with topical generics or our research in new advanced therapies. Some of our R&D projects have excelled, obtaining public grants and financial aid.

KMUi project

Development of a diagnostic test based on miRNA-574-5p as a predictive biomarker for prostaglandin E2-mediated tumors

Using a previously standardized and GLP validated analytical method for the quantification of miRNAs from plasma, we will conduct an explorative biomarker study to determine miRNA-574-5p as a non-small cell lung cancer (NSCLC) stratification marker. With miRNA-574-5p as a biomarker, we hope to establish a threshold value in blood from which a PGE2-dependent lung cancer can be predicted, and thus also the therapeutic outcome with PGE2 inhibitors.

A research project in cooperation with Technical University Darmstadt and University of Gießen since 2019; funded by KMU-innovativ of the Federal Ministry of Education and Research (BMBF).

See our publications:
FASEB BioAdvances: Validation of extracellular miRNA quantification in blood samples using RT-qPCR
BIOspectrum: Flüssigbiopsie: Standardisierte mikroRNA-Analytik – die große Chance für Biomarkerstudien?

miRNA Development

Determination of micro RNAs and RNA therapeutics in human serum and plasma under Good Laboratory Practice (GLP) conditions

Validation of the method for miRNA isolation from plasma and quantification by quantitative PCR under Good Laboratory Practice (GLP) is the basis for a standardised analysis procedure of miRNAs to provide reproducible determination of miRNA biomarkers.

A research project in cooperation with Technical University Darmstadt since 2017; funded by ZIM of the Federal Ministry of Education and Research (BMBF).

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Marche Biobank Project

PERSONALIZED MEDICINES: DRUGS, DIAGNOSTICS AND NEW THERAPEUTIC APPROACHES
Establishment of A.T.S. (Scope Temporary Association) and special collective mandate with representation for POR MARCHE FESR 2014/2020 – ASSE 1 – OS 2 – AZIONE 2.1 Support for the Development of Technological Platforms for Collaborative Research, Development and Innovation in the areas of Intelligent Specialization.

https://www.linkedin.com/company/marchebiobank/
https://www.marchebiobank.it/en/homepage/
Marche Biobank poster

Biosimilars

IMPLEMENTATION OF NEW ANALYTICAL METHODS FOR BIOSIMILARS. Decision of the CENTRO PARA EL DESARROLLO TECNOLÓGICO E INDUSTRIAL (CDTI) for a financial aid to the development of the Project IDI-20140009 dated February 3, 2014.

Biosimilares

IMPLEMENTACIÓN DE NUEVAS METODOLOGÍAS ANALÍTICAS PARA BIOSIMILARES. Resolución del CENTRO PARA EL DESARROLLO TECNOLÓGICO E INDUSTRIAL (CDTI) de ayuda financiera al desarrollo del Proyecto IDI-20140009 de fecha 3 de febrero de 2014.

Glycosaminoglycans

DEVELOPMENT OF A NEW ANALYTICAL PLATFORM FOR THERAPEUTIC GLYCOSAMINOGLYCANS. Decision EMO/1430/2015, dated June 25, 2015 (DOGC núm. 6902 de 30/06/2015) regarding the call for NUCLEUS OF INDUSTRIAL RESEARCH AND EXPERIMENTAL DEVELOPMENT (file number RD15-1-0080). This project has received funding from the European Union through the European Regional Development Fund (ERDF). With the collaboration from ACCIO.

Glicosaminoglicans

DESENVOLUPAMENT D’UNA NOVA PLATAFORMA ANALÍTICA DE GLICOSAMINOGLICANS TERAPÈUTICS. Resolució EMO/1430/2015, de 25 de juny (DOGC núm. 6902 de 30/06/2015) de convocatòria de la línia d’ajuts a NUCLIS DE RECERCA INDUSTRIAL I DESENVOLUPAMENT EXPERIMENTAL (núm. d’expedient RD15-1-0080). Aquest projecte ha estat cofinançat per la Unió Europea a través del Fons Europeu de Desenvolupament Regional (FEDER). Amb la col·laboració d’ACCIÓ.

Medical Device

Resolution EMC/1845/2016 dated 11th of July (DOGC number 7172 de 28.7.2106) regarding the call for aids in NUCLEUS OF INDUSTRIAL RESEARCH AND EXPERIMENTAL DEVELOPMENT registered with the expedient number RD16-1-0030 to grant the project BIODEGRADABLE MEDICAL DEVICE AS A TOOL FOR THERAPEUTIC IMPROVEMENT IN A LONG-TERM ILLNESS. This project has received funding from the European Union through the European Regional Development Fund (ERDF). With the collaboration from ACCIO.

Dispositiu mèdic

Resolució EMC/1845/2016 d’11 de juliol (DOGC núm. 7172 de 28.7.2106) de convocatòria de la línia d’ajuts a NUCLIS DE RECERCA INDUSTRIAL I DESENVOLUPAMENT EXPERIMENTAL, enregistrada amb el número d’expedient RD16-1-0030 que s’atorga al projecte DISPOSITIU MÈDIC BIODEGRADABLE COM A EINA DE MILLORA TERAPÈUTICA EN MALALTIA DE LLARGA DURADA. Aquest projecte ha estat cofinançat per la Unió Europea a través del Fons Europeu de Desenvolupament Regional (FEDER). Amb la col·laboració d’ACCIÓ.

Industrial PhD

Third final partial resolution of the INDUSTRIAL PHD 2017 CALL of the Agència de Gestió d’Ajuts Universitaris i de Recerca (AGAUR) of the Departament d’Empresa i Coneixement de la Generalitat de Catalunya dated 24th of November, 2017. Expedient number 2017 DI 045 on behalf of the company Kymos Pharma Services, S.L. and of the research organization Universitat Autònoma de Barcelona.

Doctorat Industrial

Tercera resolució parcial definitiva de la CONVOCATÒRIA DE DOCTORATS INDUSTRIALS (DI) 2017 de l’Agència de Gestió d’Ajuts Universitaris i de Recerca (AGAUR) del Departament d’Empresa i Coneixement de la Generalitat de Catalunya de data 24 de Novembre de 2017. Número d’expedient 2017 DI 045 en favor de l’empresa Kymos Pharma Services, S.L. i de l’organisme de recerca Universitat Autònoma de Barcelona.

High Impact

Resolution of the Agència per a la Competitivitat de l’Empresa, ACCIÓ, dated 18th of October 2017, in accordance with the Resolution EMC/1900/2017 approving the regulatory basis of the program of aids to high impact investments, and the Resolution EMC/2169/2017 openning the 2017 call, registered with the reference file number ACIAI17-1-0052: CREATION OF NEW JOBS IN THE PHARMACEUTICAL AND BIOTECHNOLOGICAL SECTOR (KREALAB).

Alt Impacte

Resolució de l’Agència per a la Competitivitat de l’Empresa, ACCIÓ, de data 18 d’octubre de 2017 d’acord amb allò disposat a la Resolució EMC/1900/2017 per la qual s’aproven les bases reguladores del programa d’ajuts a inversions d’alt impacte, i la Resolució EMC/2169/2017 per la qual s’obre la convocatòria per a l’any 2017, enregistrada amb el número d’expedient ACIAI17-1-0052: CREACIÓ DE NOUS LLOC DE TREBALL AL SECTOR FARMACÈUTIC I BIOTECNOLÒGIC (KREALAB).

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