{"id":42805,"date":"2018-07-07T13:25:50","date_gmt":"2018-07-07T11:25:50","guid":{"rendered":"https:\/\/kymos.com\/news\/%e8%82%9d%e7%b4%a0%e6%8a%97%e5%9b%a0%e5%ad%90%e6%b4%bb%e6%80%a7%e6%a3%80%e6%b5%8b\/"},"modified":"2018-07-07T13:25:50","modified_gmt":"2018-07-07T11:25:50","slug":"%e8%82%9d%e7%b4%a0%e6%8a%97%e5%9b%a0%e5%ad%90%e6%b4%bb%e6%80%a7%e6%a3%80%e6%b5%8b","status":"publish","type":"post","link":"https:\/\/kymos.com\/zh-hans\/news\/%e8%82%9d%e7%b4%a0%e6%8a%97%e5%9b%a0%e5%ad%90%e6%b4%bb%e6%80%a7%e6%a3%80%e6%b5%8b\/","title":{"rendered":"\u809d\u7d20\u6297\u56e0\u5b50\u6d3b\u6027\u68c0\u6d4b"},"content":{"rendered":"<p><span style=\"font-size: 14pt;\"><strong>\u809d\u7d20<\/strong>\u662f\u4e00\u79cd\u786b\u9178\u5316\u7cd6\u80fa\u805a\u7cd6\uff0c\u662f\u4ee5\u4e0d\u540c\u5206\u5b50\u91cf\u7684\u5f02\u8d28\u5206\u5b50\u6df7\u5408\u7269\u5f62\u5f0f\u5b58\u5728\u7684\uff0c\u5728\u533b\u5b66\u4e0a\u7528\u4f5c\u6297\u51dd\u5242\u3002\u5b83\u5b58\u5728\u4e8e\u54fa\u4e73\u52a8\u7269\u7ec4\u7ec7\u4e2d\uff0c\u901a\u5e38\u4ece\u4eba\u7c7b\u98df\u7528\u54fa\u4e73\u52a8\u7269\u7684\u80a0\u7c98\u819c\u6216\u5176\u4ed6\u5408\u9002\u7684\u7ec4\u7ec7\u4e2d\u83b7\u5f97\u3002\u5bf9\u5176\u8fdb\u884c\u7eaf\u5316\u662f\u4e3a\u4e86\u4fdd\u7559\u9488\u5bf9\u8840\u6db2\u51dd\u56fa\u5e8f\u5217\u4e0d\u540c\u90e8\u5206\u7684\u7efc\u5408\u6d3b\u6027\u3002\u5b83\u7531 D-\u8461\u7cd6\u80fa\uff08N-\u786b\u9178\u5316\u3001O-\u786b\u9178\u5316\u6216 N-\u4e59\u9170\u5316\uff09\u548c\u7cd6\u919b\u9178\uff08L-\u827e\u675c\u7cd6\u919b\u9178\u6216 D-\u8461\u7cd6\u919b\u9178\uff09\u4ea4\u66ff\u884d\u751f\u7269\u901a\u8fc7\u7cd6\u82f7\u952e\u8fde\u63a5\u800c\u6210\u7684\u805a\u5408\u7269\u7ec4\u6210\u3002\u809d\u7d20\u7684\u5206\u7ea7\u5206\u79bb\u4ea7\u751f\u4e86\u4f4e\u5206\u5b50\u91cf\u809d\u7d20 (LMWH)\uff0c\u5b83\u663e\u793a\u51fa\u4f18\u4e8e\u672a\u5206\u7ea7\u809d\u7d20\u7684\u67d0\u4e9b\u4f18\u52bf\u3002    <\/span><\/p>\n<div class=\"blog-content\">\n<div class=\"field field-name-body field-type-text-with-summary field-label-hidden\">\n<div class=\"field-items\">\n<div class=\"field-item even\">\n<h3><\/h3>\n<h3><span style=\"font-size: 14pt;\">\u8fd1\u671f\u5386\u53f2<\/span><\/h3>\n<p><span style=\"font-size: 14pt;\">\u9488\u5bf9 2007\/2008 \u5e74\u809d\u7d20\u63ba\u5047\u5371\u673a\uff08\u7531\u4e8e\u5728\u4e2d\u56fd\u5236\u9020\u7684\u539f\u6750\u6599\u4e2d\u63ba\u5165\u4e86<b>\u8fc7\u5ea6\u786b\u9178\u5316\u786b\u9178\u8f6f\u9aa8\u7d20<\/b> (OSCS)\uff0c\u5bfc\u81f4\u7f8e\u56fd\u81f3\u5c11 81 \u4eba\u6b7b\u4ea1\uff09\uff0c\u7f8e\u56fd\u548c\u6b27\u76df\u836f\u5178\u4fee\u8ba2\u4e86\u5176\u809d\u7d20\u4e13\u8bba<b>\u3002<\/b>USP32-NF27 \u548c\u6b27\u6d32\u836f\u5178\u7b2c 7<sup>\u7248<\/sup>\u7eb3\u5165\u4e86\u6b63\u4ea4\u5206\u6790\u6280\u672f\u7684\u5e94\u7528\uff0c\u5982 <strong><sup>1<\/sup>H-NMR<\/strong>\u3001<strong>\u9634\u79bb\u5b50\u4ea4\u6362\u8272\u8c31\u6cd5<\/strong>\u548c<strong>\u6bdb\u7ec6\u7ba1\u7535\u6cf3<\/strong>\uff0c\u4ee5\u786e\u8ba4\u4e0d\u5b58\u5728 OSCS\u3002\u6b64\u5916\uff0c\u4e4b\u524d\u5728\u7ef5\u7f8a\u8840\u6d46\u4e2d\u8fdb\u884c\u7684\u51dd\u8840\u6d4b\u5b9a\u88ab\u66f4\u5177\u7279\u5f02\u6027\u7684<strong>\u6297\u56e0\u5b50 IIa \u6d3b\u6027<\/strong>\u548c<strong>\u6297\u56e0\u5b50 Xa \u6d3b\u6027<\/strong>\u6d4b\u5b9a\u6240\u53d6\u4ee3\u3002  <\/span><\/p>\n<h3><\/h3>\n<h3><span style=\"font-size: 14pt;\">\u68c0\u6d4b\u7684\u79d1\u5b66\u4f9d\u636e<\/span><\/h3>\n<p><span style=\"font-size: 14pt;\">\u56e0\u5b50 Xa \u548c\u56e0\u5b50 IIa\uff08\u6216\u51dd\u8840\u9176\uff09\u662f\u6c34\u89e3\u86cb\u767d\u6216\u80bd\u9176\uff0c\u5728\u51dd\u8840\u7ea7\u8054\u53cd\u5e94\u7684\u6700\u7ec8\u5171\u540c\u9014\u5f84\u4e2d\u53d1\u6325\u4f5c\u7528\u3002\u56e0\u5b50 Xa \u4ecb\u5bfc\u51dd\u8840\u9176\u539f\u5411\u56e0\u5b50 II \u7684\u8f6c\u5316\u3002\u540c\u65f6\uff0c\u56e0\u5b50 II \u4ecb\u5bfc\u53ef\u6eb6\u6027\u7ea4\u7ef4\u86cb\u767d\u539f\u5411\u4e0d\u6eb6\u6027\u7ea4\u7ef4\u86cb\u767d\u7684\u8f6c\u5316\uff0c\u4ece\u800c\u5f62\u6210\u8840\u5757\u3002  <\/span><\/p>\n<p class=\"rtecenter\"><span style=\"font-size: 14pt;\"><b>\u51dd\u8840\u9176\u539f + \u56e0\u5b50 Xa \u2192 \u56e0\u5b50 IIa<\/b><\/span><\/p>\n<p class=\"rtecenter\"><span style=\"font-size: 14pt;\"><b>\u7ea4\u7ef4\u86cb\u767d\u539f + \u56e0\u5b50 IIa \u2192 \u7ea4\u7ef4\u86cb\u767d\uff08\u8840\u5757\uff09 <\/b><\/span><\/p>\n<p><span style=\"font-size: 14pt;\">\u56e0\u5b50 IIa \u548c Xa \u7684\u6d3b\u6027\u53d7\u6297\u51dd\u8840\u9176 (AT) \u6291\u5236\uff0c\u4ece\u800c\u8c03\u8282\u51dd\u8840\u7ea7\u8054\u53cd\u5e94\uff1aAT \u6d3b\u6027\u7684\u589e\u52a0\u4f1a\u5bfc\u81f4\u51dd\u8840\u51cf\u5c11\uff0c\u53cd\u4e4b\u4ea6\u7136\u3002\u809d\u7d20\u4e0e AT \u7ed3\u5408\u4ea7\u751f\u6784\u8c61\u53d8\u5316\uff0c\u4ece\u800c\u589e\u5f3a\u5176\u5bf9\u56e0\u5b50 IIa \u548c Xa \u7684\u6291\u5236\u4f5c\u7528\u3002\u8fd9\u79cd\u5bf9\u8fd9\u4e9b\u80bd\u9176\u6291\u5236\u7ed3\u679c\u7684\u589e\u5f3a\u4f5c\u7528\u5bfc\u81f4\u4e86\u809d\u7d20\u5728\u836f\u7406\u5e94\u7528\u4e2d\u7684\u6297\u51dd\u6548\u679c\u3002\u4f4e\u5206\u5b50\u91cf\u809d\u7d20\u50ac\u5316\u56e0\u5b50 IIa \u4e0e\u6297\u51dd\u8840\u9176\u4e4b\u95f4\u53cd\u5e94\u7684\u80fd\u529b\u4e0d\u5982\u6d89\u53ca<b>\u56e0\u5b50 Xa<\/b> \u7684\u53cd\u5e94\u3002\u76f8\u53cd\uff0c\u666e\u901a\u809d\u7d20\uff08\u672a\u5206\u7ea7\u809d\u7d20\uff09\u5bf9\u8fd9\u4e24\u79cd\u53cd\u5e94\u7684\u50ac\u5316\u4f5c\u7528\u76f8\u540c\u3002    <\/span><\/p>\n<h3><\/h3>\n<h3><span style=\"font-size: 14pt;\">Kymos \u7684\u8d21\u732e<\/span><\/h3>\n<p><span style=\"font-size: 14pt;\">\u5e02\u552e\u8bd5\u5242\u76d2\u5e76\u4e0d\u603b\u662f\u6700\u4f73\u89e3\u51b3\u65b9\u6848\uff0c\u53ef\u80fd\u9700\u8981\u6839\u636e\u809d\u7d20\u7684\u6765\u6e90\u3001\u6d53\u5ea6\u3001\u6c61\u67d3\u7269\u548c\u5176\u4ed6\u56e0\u7d20\u8fdb\u884c\u6539\u8fdb\u3002\u836f\u5178\u6807\u51c6\u68c0\u6d4b\u7684\u5b9e\u65bd\u4e5f\u8f83\u4e3a\u590d\u6742\uff0c\u5373\u4f7f\u662f\u5728\u5177\u6709\u6b64\u7c7b\u68c0\u6d4b\u7ecf\u9a8c\u7684\u5b9e\u9a8c\u5ba4\u4e2d\u4e5f\u662f\u5982\u6b64\uff0c\u56e0\u6b64\u5efa\u8bae\u8fdb\u884c\u65b9\u6cd5\u9a8c\u8bc1\u3002Kymos \u5df2\u7ecf\u5f00\u53d1\u5e76\u9a8c\u8bc1\u4e86\u7b26\u5408\u6b27\u6d32\u836f\u5178 (Eur. Ph.) \u548c\u7f8e\u56fd\u836f\u5178 (USP) \u7684\u65b9\u6cd5\uff0c\u5e76\u5728\u7b26\u5408 GMP \u89c4\u8303\u7684\u60c5\u51b5\u4e0b\u63d0\u4f9b\u68c0\u6d4b\u670d\u52a1\u3002\u4e86\u89e3\u66f4\u591a\u5173\u4e8e\u6211\u4eec\u7684<a href=\"https:\/\/kymos.com\/zh-hans\/%e6%9c%8d%e5%8a%a1%e9%a1%b9%e7%9b%ae\/cmc-%e5%88%86%e6%9e%90%e4%b8%8e%e8%b4%a8%e9%87%8f%e6%8e%a7%e5%88%b6\/%e7%94%9f%e7%89%a9%e5%88%b6%e5%93%81%e5%92%8c%e7%94%9f%e7%89%a9%e7%b1%bb%e4%bc%bc%e8%8d%af%e7%9a%84%e8%b4%a8%e9%87%8f%e6%8e%a7%e5%88%b6\/\" data-wpel-link=\"internal\">\u751f\u7269\u5236\u54c1\u548c\u751f\u7269\u7c7b\u4f3c\u836f GMP \u670d\u52a1<\/a>\u3002    <\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u809d\u7d20\u662f\u4e00\u79cd\u786b\u9178\u5316\u7cd6\u80fa  [&#8230;]<\/p>\n","protected":false},"author":7,"featured_media":42806,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[381],"tags":[],"class_list":["post-42805","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cmc"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>\u809d\u7d20\u6297\u56e0\u5b50\u6d3b\u6027\u68c0\u6d4b - Kymos<\/title>\n<meta name=\"description\" content=\"Kymos \u6839\u636e\u6b27\u6d32\u836f\u5178 (Eur. 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