{"id":42756,"date":"2021-06-28T16:58:15","date_gmt":"2021-06-28T14:58:15","guid":{"rendered":"https:\/\/kymos.com\/news\/%e6%90%ba%e6%89%8b%e6%88%90%e9%95%bf-20-%e8%bd%bd\/"},"modified":"2026-07-07T12:54:09","modified_gmt":"2026-07-07T10:54:09","slug":"%e6%90%ba%e6%89%8b%e6%88%90%e9%95%bf-20-%e8%bd%bd","status":"publish","type":"post","link":"https:\/\/kymos.com\/zh-hans\/news\/%e6%90%ba%e6%89%8b%e6%88%90%e9%95%bf-20-%e8%bd%bd\/","title":{"rendered":"\u643a\u624b\u6210\u957f 20 \u8f7d"},"content":{"rendered":"

Kymos \u4e0e PharmaMar \u7684\u6545\u4e8b\uff1a\u4e00\u6bb5\u534f\u4f5c\u4e0e\u6210\u529f\u7684\u65c5\u7a0b<\/span><\/h2>\n

\u5728\u62a5\u544a\u4e86\u53f2\u4e0a\u6700\u4f73\u8425\u6536\u5e76\u6210\u4e3a\u6210\u529f\u7684\u8de8\u56fd\u96c6\u56e2\u540e\uff0c\u80fd\u591f\u5e86\u795d\u5408\u4f5c 20 \u5468\u5e74\u7684\u516c\u53f8\u5e76\u4e0d\u591a\uff0c\u4f46\u5408\u540c\u7814\u7a76\u7ec4\u7ec7 KYMOS \u548c\u9876\u7ea7\u751f\u7269\u5236\u836f\u521b\u65b0\u8005 PHARMAMAR<\/a> \u6b63\u51c6\u5907\u8fd9\u6837\u505a\u3002 <\/span><\/p>\n

\u8fc7\u53bb\u4e8c\u5341\u5e74\u95f4\u533b\u836f\u5916\u5305\u7684\u6f14\u53d8\u5982\u4f55\u6539\u53d8\u4e86\u8fd9\u4e24\u4f4d\u8001\u4f19\u4f34\u7684\u53d1\u5c55\u8f68\u8ff9\uff0c\u662f\u4e00\u4e2a\u503c\u5f97\u9605\u8bfb\u7684\u6545\u4e8b\u3002 <\/span><\/p>\n

Kymos \u8054\u5408\u521b\u59cb\u4eba\u517c\u57fa\u5730\u603b\u7ecf\u7406 Llu\u00efsa Garc\u00eda \u535a\u58eb\u4e0e PharmaMar \u975e\u4e34\u5e8a\u6bd2\u7406\u5b66\u548c\u836f\u7406\u5b66\u7ecf\u7406 Pablo Avil\u00e9s \u535a\u58eb\u5171\u805a\u4e00\u5802\uff0c\u56de\u987e\u81ea 2001 \u5e74\u4ee5\u6765\u6211\u4eec\u6240\u53d6\u5f97\u7684\u6240\u6709\u6210\u5c31\u3002<\/span><\/p>\n

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\u201c\u5728\u6210\u4e3a\u5408\u540c\u7814\u7a76\u7ec4\u7ec7 <\/i><\/span>(CRO) \u4e4b\u524d\uff0c\u6211\u4eec\u6700\u521d\u662f\u7f8e\u7eb3\u91cc\u5c3c (Menarini) \u7814\u53d1\u56e2\u961f\u7684\u4e00\u90e8\u5206\uff0c\u53c2\u4e0e\u4e86\u836f\u7269\u5f00\u53d1\u8fc7\u7a0b\u7684\u6240\u6709\u6b65\u9aa4\uff1a\u4ece\u836f\u7269\u53d1\u73b0\u5230\u5546\u4e1a\u5316<\/i><\/span>\u3002\u201d Garc\u00eda \u535a\u58eb\u5f00\u59cb\u8bf4\u9053\u3002\u201c<\/span>\u4ece Kymos \u6210\u7acb\u4e4b\u521d\uff0c\u6211\u4eec\u5c31\u5df2\u7ecf\u719f\u6089\u5ba2\u6237\u6240\u9700\u7684\u6240\u6709\u670d\u52a1\u3002\u5982\u679c\u6211\u4eec\u7684\u5ba2\u6237\u9047\u5230\u95ee\u9898\uff0c\u6211\u4eec\u603b\u662f\u5c1d\u8bd5\u63d0\u4f9b\u5e2e\u52a9\uff0c\u5c31\u50cf\u6211\u4eec\u662f\u4ed6\u4eec\u81ea\u5df1\u7814\u53d1\u90e8\u95e8\u7684\u5ef6\u4f38\u4e00\u6837 <\/i><\/span>\u3002\u201d<\/span><\/p>\n

\u4f46 21 \u4e16\u7eaa\u521d\u65b0\u5174\u7684\u5e02\u573a\u8d8b\u52bf\u5f88\u5feb\u5bf9 Kymos \u4f5c\u4e3a CRO \u7684\u6f14\u53d8\u4ee5\u53ca PharmaMar \u7b49\u5236\u836f\u516c\u53f8\u5bf9\u5176\u7684\u770b\u6cd5\u4ea7\u751f\u4e86\u6df1\u8fdc\u5f71\u54cd\u3002Pablo Avil\u00e9s \u535a\u58eb\u5206\u4eab\u4e86\u4ed6\u7684\u89c2\u70b9\uff1a <\/span><\/p>\n

\u201c\u90a3\u65f6\u7684\u4f01\u4e1a\u836f\u7269\u5f00\u53d1\u975e\u5e38\u4e0d\u540c\u3002<\/i>\u201d Avil\u00e9s \u535a\u58eb\u5f00\u59cb\u8bf4\u9053\u3002\u201c\u5728\u90a3\u4e2a\u5e74\u4ee3\uff0c\u666e\u904d\u7684\u8d8b\u52bf\u662f\u5c06\u5927\u90e8\u5206\u4efb\u52a1\u7559\u5728\u5185\u90e8\u5b8c\u6210\uff0c\u4f46\u8fd9\u53ea\u80fd\u4ee5\u5de8\u5927\u7684\u6210\u672c\u6765\u5b9e\u73b0\u3002\u7136\u800c\uff0c\u5bf9\u6a21\u5f0f\u7684\u5f7b\u5e95\u91cd\u65b0\u601d\u8003\u4fc3\u4f7f\u6211\u4eec\u5c06\u67d0\u4e9b\u4efb\u52a1\u5916\u5305\u7ed9\u50cf Kymos \u8fd9\u6837\u7684 CRO\u3002\u4ed6\u4eec\u4e0d\u4ec5\u80fd\u4ee5\u66f4\u4f4e\u7684\u6210\u672c\u8fdb\u884c\u68c0\u6d4b\uff0c\u800c\u4e14\u7531\u4e8e\u63a5\u89e6\u8fc7\u5982\u6b64\u591a\u4e0d\u540c\u7684\u5ba2\u6237\u3001\u836f\u7406\u5316\u5408\u7269\u548c\u6cbb\u7597\u9886\u57df\uff0c\u4ed6\u4eec\u8fd8\u80fd\u63d0\u4f9b\u5353\u8d8a\u7684\u5386\u53f2\u7ecf\u9a8c\u548c\u4e13\u4e1a\u77e5\u8bc6\u3002\u4ed6\u4eec\u89e3\u51b3\u5e76\u9884\u89c1\u5230\u4e86\u975e\u5e38\u591a\u6837\u5316\u7684\u95ee\u9898\u3002\u201d <\/i><\/span><\/p>\n

\u6269\u5c55\u80fd\u529b<\/span><\/h2>\n

\u201c\u5bf9\u4e8e CMC \u6d3b\u52a8\u6765\u8bf4\u5c24\u5176\u5982\u6b64<\/i>\u201d Garc\u00eda \u535a\u58eb\u7ee7\u7eed\u8bf4\u9053\u3002\u201c\u8d77\u521d\uff0c\u5f53\u5730\u8d5e\u52a9\u5546\u53ea\u8003\u8651\u5916\u5305\u4e34\u5e8a\u524d\u548c\u4e34\u5e8a\u751f\u7269\u5206\u6790\uff0c\u800c CMC \u5927\u591a\u5728\u5185\u90e8\u8fdb\u884c\u3002\u6211\u4eec\u9996\u5148\u4e13\u6ce8\u4e8e\u7814\u53d1\uff0c\u4f46\u5f88\u5feb\u6269\u5c55\u5230\u8d28\u91cf\u63a7\u5236\u548c\u7a33\u5b9a\u6027\u7814\u7a76\uff1a\u901a\u8fc7\u4e0e PharmaMar \u7684\u5408\u4f5c\uff0c\u751f\u7269\u5206\u6790\u4e5f\u8ba9\u4f4d\u4e8e\u7eaf\u5316\u4f18\u5316\u3001\u4f53\u5916\u4ee3\u8c22\u3001\u4eba\u5fae\u7c92\u4f53\u5236\u5907\u3001\u7ed3\u6784\u9274\u5b9a\u7b49\u3002\u6211\u4eec\u6574\u5408\u7684\u751f\u7269\u5206\u6790\/CMC \u7ec4\u5408\u5e26\u6765\u4e86\u610f\u60f3\u4e0d\u5230\u7684\u63d0\u5347\uff0c\u5e76\u63d0\u4f9b\u4e86\u4f18\u4e8e\u5176\u4ed6 CRO \u7684\u7ade\u4e89\u4f18\u52bf <\/i>\u3002\u201d<\/span><\/p>\n

\u5f53\u88ab\u95ee\u53ca\u8fd9 20 \u5e74\u6210\u529f\u5408\u4f5c\u4f19\u4f34\u5173\u7cfb\u7684\u79d8\u8bc0\u65f6\uff0cPablo Avil\u00e9s \u89e3\u91ca\u4e86\u5728\u4ed6\u7684\u5de5\u4f5c\u4e2d\u2014\u2014\u53d1\u73b0\u548c\u5f00\u53d1\u4ece\u6d77\u6d0b\u751f\u7269\u4e2d\u63d0\u53d6\u7684\u6297\u80bf\u7624\u5019\u9009\u836f\u7269\u2014\u2014\u4ed6\u5bf9 CRO \u5408\u4f5c\u4f19\u4f34\u5bc4\u4e88\u539a\u671b\uff1a<\/span><\/p>\n

\u201c\u8fde\u7eed\u6027\u662f\u5173\u952e<\/i>\u201d Avil\u00e9s \u535a\u58eb\u89e3\u91ca\u9053\u3002\u201c\u57fa\u7840\u751f\u7269\u5206\u6790\u7814\u53d1\u9700\u8981\u975e\u5e38\u7a33\u5065\u7684\u65b9\u6cd5\uff0c\u4ee5\u786e\u4fdd\u540e\u7eed\u5411\u751f\u7269\u5206\u6790\u5e08\u3001\u975e\u4e34\u5e8a\u6bd2\u7406\u5b66\u5bb6\u548c I \u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u5e73\u7a33\u8fc7\u6e21\u3002Kymos \u5728\u975e\u4e34\u5e8a\u9636\u6bb5\u7684\u4e13\u4e1a\u77e5\u8bc6\u548c\u95ee\u9898\u89e3\u51b3\u80fd\u529b\u5e2e\u52a9\u6211\u4eec\u8bbe\u8ba1\u4e86\u66f4\u9002\u5408\u5b9e\u65bd\u7684\u65b9\u6cd5\uff0c\u4f7f\u6211\u4eec\u80fd\u591f\u5728\u4e34\u5e8a\u9636\u6bb5\u8fdb\u5c55\u5f97\u66f4\u5feb\u3002\u8fd9\u4e00\u5207\u90fd\u5f52\u529f\u4e8e\u771f\u6b63\u7684\u53cc\u8fb9\u56e2\u961f\u5408\u4f5c <\/i>\uff0c\u201d\u4ed6\u7ee7\u7eed\u8bf4\u9053\uff0c\u201cKymos \u901a\u8fc7\u6211\u4eec\u7684\u6295\u5165\u5b66\u4e60\u5316\u5408\u7269\u5904\u7406\uff0c\u800c\u6211\u4eec\u53ef\u4ee5\u5728\u540e\u671f\u66f4\u590d\u6742\u7684\u5f00\u53d1\u9636\u6bb5\u66f4\u597d\u5730\u9884\u89c1\u95ee\u9898<\/i>\u3002\u201d<\/span><\/p>\n

\u4eca\u5929\uff0cKymos \u5e86\u795d\u5176\u6210\u7acb 20 \u5468\u5e74\uff0c\u8fd9\u6b63\u662f\u4e24\u4f4d\u5408\u4f5c\u4f19\u4f34\u56de\u987e\u5e76\u53cd\u601d\u8fc7\u53bb\u51e0\u5341\u5e74\u5171\u540c\u8d70\u8fc7\u7684\u65c5\u7a0b\u7684\u597d\u65f6\u673a\u3002\u8fd9\u662f\u4e00\u6761\u5145\u6ee1\u975e\u51e1\u6210\u5c31\u4ee5\u53ca\u5bf9\u521b\u65b0\u548c\u591a\u6837\u5316\u575a\u5b9a\u627f\u8bfa\u7684\u9053\u8def\uff1a<\/span><\/p>\n

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\u800c Avil\u00e9s \u535a\u58eb\u7684\u6545\u4e8b\u540c\u6837\u4ee4\u4eba\u7fa1\u6155\uff0c\u751a\u81f3\u66f4\u80dc\u4e00\u7b79\uff1a\u201cPharmaMar \u5df2\u7ecf\u80fd\u591f\u6ce8\u518c\u4e09\u79cd\u6297\u764c\u4ea7\u54c1\uff1aYONDELIS\u00ae\uff08\u66f2\u8d1d\u66ff\u5b9a\uff09\uff0c\u5728\u7f8e\u56fd\u548c\u6b27\u76df\u6ce8\u518c\u7528\u4e8e\u6cbb\u7597\u8089\u7624\u548c\u5375\u5de2\u764c\uff0c\u5e76\u5df2\u5728 80 \u591a\u4e2a\u56fd\u5bb6\u4e0a\u5e02\uff1bAPLIDIN\u00ae\uff08\u666e\u5229\u66ff\u5b9a\uff09\uff0c\u5728\u6fb3\u5927\u5229\u4e9a\u6ce8\u518c\u7528\u4e8e\u6cbb\u7597\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\uff0c\u76ee\u524d\u6b63\u5728\u8fdb\u884c\u9488\u5bf9 SARS-CoV-2 \u7684\u6d4b\u8bd5\uff1b\u4ee5\u53ca ZEPZELCA\u00ae\uff08\u9c81\u6bd4\u66ff\u5b9a\uff09\uff0c\u5728\u7f8e\u56fd\u6ce8\u518c\u7528\u4e8e\u6cbb\u7597 SCLC\uff0c\u8fd9\u662f\u897f\u73ed\u7259\u4ea7\u54c1\u9996\u6b21\u83b7\u5f97 FDA \u52a0\u901f\u6279\u51c6\u3002\u81ea 1996 \u5e74 FDA \u6279\u51c6\u8be5\u9886\u57df\u7684\u6700\u540e\u4e00\u4e2a\u5316\u5b66\u5b9e\u4f53\u4ee5\u6765\uff0c\u8fd9\u4e00\u9002\u5e94\u75c7\u7684\u6cbb\u7597\u5728 20 \u591a\u5e74\u91cc\u51e0\u4e4e\u6ca1\u6709\u53d8\u5316\u3002\u6700\u91cd\u8981\u7684\u662f\uff0c2020 \u5e74\u662f\u516c\u53f8\u5386\u53f2\u4e0a\u6700\u597d\u7684\u4e00\u5e74\uff0c\u603b\u8425\u6536\u8fbe 2.7 \u4ebf\u6b27\u5143\uff1b\u6bd4 2019 \u5e74\u589e\u957f\u4e86 215%\u3002\u6211\u6000\u7591\u6ca1\u6709\u591a\u5c11\u50cf\u6211\u4eec\u8fd9\u6837\u89c4\u6a21\u7684\u516c\u53f8\u80fd\u8bf4\u540c\u6837\u7684\u8bdd <\/i>\u201d Avil\u00e9s \u535a\u58eb\u5ba3\u79f0\uff0c\u201c\u800c\u4e14\u8fd9\u662f\u57fa\u4e8e\u4e00\u4e2a\u5b8c\u5168\u521b\u65b0\u7684\u524d\u63d0\uff0c\u5373\u4ece\u6d77\u6d0b\u751f\u7269\u4e2d\u5f00\u53d1\u836f\u7269\u3002<\/i>\u201d<\/span><\/p>\n

\u5c55\u671b\u672a\u6765\uff1a\u521b\u65b0\u4e0e\u534f\u4f5c\u7684\u672a\u6765<\/b><\/span><\/p>\n

PharmaMar \u548c Kymos \u786e\u5b9e\u8868\u73b0\u51fa\u4e86\u826f\u597d\u7684\u534f\u540c\u6548\u5e94\uff0c\u9996\u5148\u4ece\u5404\u81ea\u7684\u9996\u5e2d\u6267\u884c\u5b98 Jos\u00e9 Mar\u00eda Fern\u00e1ndez Sousa-Faro \u535a\u58eb\u548c Joan Puig de Dou \u5f00\u59cb\uff0c\u4e24\u4eba\u90fd\u62e5\u6709\u6df1\u539a\u7684\u79d1\u5b66\u80cc\u666f\uff0c\u5e76\u51c6\u5907\u5728\u672a\u6765\u7ee7\u7eed\u4e13\u6ce8\u4e8e\u521b\u65b0\u3002\u4e8b\u5b9e\u4e0a\uff0c\u4eba\u4eec\u4e0d\u7981\u60f3\u77e5\u9053\u672a\u6765\u4e3a\u4ed6\u4eec\u51c6\u5907\u4e86\u4ec0\u4e48\u3002\u6bd5\u7adf\uff0c\u5468\u5e74\u7eaa\u5ff5\u662f\u56de\u987e\u8fc7\u53bb\u4e5f\u662f\u5c55\u671b\u672a\u6765\u7684\u597d\u65f6\u673a\u3002Llu\u00efsa Garc\u00eda \u535a\u58eb\u9996\u5148\u8bc4\u8bba\u9053\uff1a <\/span><\/p>\n

\u201c\u81ea\u6211\u4eec\u5728\u5df4\u585e\u7f57\u90a3\u79d1\u5b66\u56ed (PCB) \u521b\u4e1a\u4ee5\u6765\uff0c\u6211\u4eec\u5df2\u7ecf\u8d70\u8fc7\u4e86\u6f2b\u957f\u7684\u9053\u8def\uff0c\u770b\u5230\u6211\u4eec\u7684\u5ba2\u6237\u4e0e\u6211\u4eec\u7684\u4e1a\u52a1\u4e00\u8d77\u6210\u957f\u662f\u975e\u5e38\u4ee4\u4eba\u6b23\u6170\u7684\u3002\u5728\u65b0\u95fb\u4e2d\u542c\u5230\u6211\u4eec PharmaMar \u670b\u53cb\u7684\u6d88\u606f\u603b\u662f\u4ee4\u4eba\u5174\u594b <\/i>\u201d\u5979\u70ed\u60c5\u5730\u8865\u5145\u9053\u3002\u201c\u4e24\u5bb6\u516c\u53f8\u90fd\u53c2\u4e0e\u4e86\u65b0\u7684\u5148\u8fdb\u7597\u6cd5\u7814\u7a76\uff0c\u5305\u62ec\u57fa\u56e0\u6c89\u9ed8\u3001\u6cbb\u7597\u6027 RNA \u4ee5\u53ca\u65b0\u7684 COVID-19 \u7597\u6cd5\u5f00\u53d1\u3002Kymos \u5c06\u4e3a\u80fd\u7ee7\u7eed\u4e0e PharmaMar \u96c6\u56e2\u5728\u5176\u591a\u4e2a\u4e34\u5e8a\u524d\u548c\u4e34\u5e8a\u9636\u6bb5\u9879\u76ee\u4e2d\u5408\u4f5c\u800c\u611f\u5230\u81ea\u8c6a\u3002 <\/i>\u201d<\/span><\/p>\n

Avil\u00e9s \u535a\u58eb\u63a5\u8fc7\u4e86 Garc\u00eda \u535a\u58eb\u7684\u8bdd\u5934\uff1a\u201c\u81ea\u6210\u7acb\u4ee5\u6765\uff0cPharmaMar \u5c31\u627f\u8bfa\u5c3d\u53ef\u80fd\u591a\u5730\u4e3a\u65b0\u5316\u5408\u7269\u5f15\u5165 I \u671f\u4e34\u5e8a\u3002\u9664\u4e86\u6211\u4eec\u7684\u65d7\u8230\u836f\u7269\u5916\uff0c\u6211\u4eec\u8fd8\u5728\u5168\u7403\u8303\u56f4\u5185\u542f\u52a8\u4e86\u591a\u9879\u65b0\u7684\u4e34\u5e8a\u5f00\u53d1\u5e76\u8d44\u52a9\u4e86\u591a\u9879\u7814\u7a76\uff0c\u5305\u62ec\u4e00\u4e2a\u65b0\u7684\u75c5\u6bd2\u5b66\u90e8\u95e8\u3001\u666e\u5229\u66ff\u5b9a\u7684\u6297\u75c5\u6bd2\u91cd\u65b0\u5b9a\u4f4d\u4ee5\u53ca\u4eca\u5e74\u8fdb\u5165 I \u671f\u7684\u4e24\u79cd\u65b0\u5316\u5408\u7269\u3002\u8fd9\u4e00\u5de8\u5927\u7684\u52aa\u529b\u662f\u6211\u4eec\u6210\u957f\u7684\u5173\u952e\uff0c\u4f46\u5982\u679c\u6ca1\u6709\u50cf Kymos \u8fd9\u6837\u9ad8\u4ef7\u503c\u5408\u4f5c\u4f19\u4f34\u7684\u652f\u6301\uff0c\u8fd9\u4e00\u5207\u90fd\u662f\u4e0d\u53ef\u80fd\u5b9e\u73b0\u7684 <\/i>\u201d\u4ed6\u603b\u7ed3\u9053\u3002<\/span><\/p>\n

\u4e8c\u5341\u5e74\u662f\u4e00\u6bb5\u5f88\u957f\u7684\u7ecf\u8425\u65f6\u95f4\uff0c\u5c24\u5176\u662f\u5728\u5236\u836f\u8fd9\u6837\u4e00\u4e2a\u4e0d\u65ad\u6f14\u53d8\u7684\u884c\u4e1a\uff0c\u4f46\u5bf9\u4e8e\u6211\u4eec\u4e24\u4f4d\u5145\u6ee1\u4fe1\u5fc3\u7684\u53d1\u8a00\u4eba\u6765\u8bf4\uff0c\u8fd9\u4f3c\u4e4e\u53ea\u662f\u8f6c\u77ac\u4e4b\u95f4\u3002\u5728\u8fd9\u6b21\u91c7\u8bbf\u4e2d\uff0c\u6211\u4eec\u6709\u673a\u4f1a\u4e86\u89e3\u4e86\u533b\u836f\u5916\u5305\u7684\u6f14\u53d8\u3001\u591a\u6837\u5316\u548c\u521b\u65b0\u7684\u529b\u91cf\uff0c\u6700\u91cd\u8981\u7684\u662f\uff0c\u4e86\u89e3\u4e86\u4e24\u5bb6\u5728\u6b63\u786e\u65f6\u95f4\u76f8\u9047\u5e76\u6210\u529f\u5171\u540c\u6210\u957f\u7684\u516c\u53f8\u7684\u52b1\u5fd7\u6545\u4e8b\u3002 <\/span>
\n\u795d\u613f\u518d\u521b 20 \u5e74\u8f89\u714c\uff01<\/span><\/p>\n

\u795d\u613f\u518d\u521b 20 \u5e74\u8f89\u714c\uff01<\/span><\/h3>\n

PharmaMar \u662f\u53d1\u73b0\u6d77\u6d0b\u6e90\u6297\u80bf\u7624\u836f\u7269\u7684\u5168\u7403\u751f\u7269\u5236\u836f\u9886\u5bfc\u8005\u3002PharmaMar \u65d7\u4e0b\u62e5\u6709\u5206\u5b50\u8bca\u65ad\u516c\u53f8 GENOMICA \u548c\u81f4\u529b\u4e8e\u6cbb\u7597\u6027\u57fa\u56e0\u6c89\u9ed8\u7814\u53d1\u7684 SYLENTIS\u3002\u6b32\u4e86\u89e3\u66f4\u591a\u5173\u4e8e PharmaMar \u7684\u4fe1\u606f\uff0c\u8bf7\u8bbf\u95ee www.pharmamar.com<\/strong><\/a>\u3002 <\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div>

\"KYMOS<\/div><\/div>

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