{"id":28219,"date":"2024-10-15T12:24:57","date_gmt":"2024-10-15T10:24:57","guid":{"rendered":"https:\/\/kymos.com\/news\/mirna-%eb%b6%84%ec%84%9d-%ea%b8%b0%ec%b4%88-%ec%97%b0%ea%b5%ac%ec%97%90%ec%84%9c-%ec%a0%9c%ed%92%88-%ed%98%81%ec%8b%a0%ea%b9%8c%ec%a7%80\/"},"modified":"2024-10-15T12:24:57","modified_gmt":"2024-10-15T10:24:57","slug":"mirna-%eb%b6%84%ec%84%9d-%ea%b8%b0%ec%b4%88-%ec%97%b0%ea%b5%ac%ec%97%90%ec%84%9c-%ec%a0%9c%ed%92%88-%ed%98%81%ec%8b%a0%ea%b9%8c%ec%a7%80","status":"publish","type":"post","link":"https:\/\/kymos.com\/ko\/news\/mirna-%eb%b6%84%ec%84%9d-%ea%b8%b0%ec%b4%88-%ec%97%b0%ea%b5%ac%ec%97%90%ec%84%9c-%ec%a0%9c%ed%92%88-%ed%98%81%ec%8b%a0%ea%b9%8c%ec%a7%80\/","title":{"rendered":"miRNA \ubd84\uc11d: \uae30\ucd08 \uc5f0\uad6c\uc5d0\uc11c \uc81c\ud488 \ud601\uc2e0\uae4c\uc9c0"},"content":{"rendered":"

2024\ub144 \ub178\ubca8 \uc0dd\ub9ac\uc758\ud559\uc0c1\uc740<\/a> \ud55c\ub54c \uac04\uacfc\ub418\uc5c8\ub358 \ubd84\uc790, \ub9c8\uc774\ud06c\ub85cRNA(miRNA)\uc5d0 \ub300\ud55c \uc624\ub79c \uc219\uc6d0\uc744 \uc774\ub8e8\uac8c \ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc62c\ud574 \ub178\ubca8 \uc0dd\ub9ac\uc758\ud559\uc0c1\uc740 \ub9c8\uc774\ud06c\ub85cRNA\uc758 \ubc1c\uacac \ubc0f \ud2b9\uc131 \uaddc\uba85\uacfc \uc720\uc804\uc790 \ubc1c\ud604 \uc870\uc808\uc5d0 \uc788\uc5b4\uc11c\uc758 \uc5ed\ud560\uc744 \uacf5\ub85c\ub85c \ube45\ud130 \uc554\ube0c\ub85c\uc2a4(Victor Ambros)\uc640 \uac8c\ub9ac \ub8e8\ube0c\ucfe4(Gary Ruvkun) \uacfc\ud559\uc790 \uacb8 \uc5f0\uad6c\uc790\uc5d0\uac8c \uc218\uc5ec\ub418\uc5c8\uc2b5\ub2c8\ub2e4. <\/span><\/p>\n

\uc218\uc2ed \ub144 \ub3d9\uc548 miRNA\ub294 “\uc0dd\ubb3c\ud559\uc801 \ud3d0\uae30\ubb3c”\ub85c \uce58\ubd80\ub418\uc5b4 \uae30\ub2a5\uc801 \uc911\uc694\uc131\uc774 \uac70\uc758 \uc5c6\ub2e4\uace0 \uc5ec\uaca8\uc84c\uc2b5\ub2c8\ub2e4. \ud558\uc9c0\ub9cc \uc624\ub298\ub0a0 \uc5f0\uad6c\uc790\ub4e4\uc774 \uc774\ub7ec\ud55c \uc18c\ubd84\uc790\ub4e4\uc774 \uc9c8\ubcd1\uc5d0 \uc5b4\ub5bb\uac8c \uc601\ud5a5\uc744 \ubbf8\uce58\uac70\ub098 \uc720\uc804\uc801 \ubc14\uc774\uc624\ub9c8\ucee4\ub85c \uc791\uc6a9\ud558\ub294\uc9c0\uc5d0 \ub300\ud574 \ub354 \uae4a\uc774 \uc774\ud574\ud568\uc5d0 \ub530\ub77c, miRNA\ub294 \uc9c4\ub2e8 \ubc0f \uce58\ub8cc \ud601\uc2e0\uc758 \uc911\uc2ec\uc774 \ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. <\/span><\/p>\n

\uc800\ud76c \ub3c5\uc77c \uc0ac\uc774\ud2b8(\uad6c Prolytic)\ub294 2016\ub144\ubd80\ud130 miRNA \uc0dd\ubb3c\ubd84\uc11d \ubd84\uc57c\uc758 \uc120\uad6c\uc790 \uc5ed\ud560\uc744 \ud574\uc654\uc2b5\ub2c8\ub2e4. \ub530\ub77c\uc11c GLP \uc9c0\uce68\uc5d0 \ub530\ub77c miRNA\ub97c \uc815\ub7c9\ud654\ud558\ub294 \ubc29\ubc95\uc744 \uac1c\ubc1c\ud558\uace0 \uac80\uc99d\ud558\uc5ec \uc774 \ubd84\uc57c\uc758 \ud601\uc2e0 \uae30\uc5c5\uc73c\ub85c \uc790\ub9ac\ub9e4\uae40\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. <\/span><\/p>\n

\uc774 \uae00\uc5d0\uc11c\ub294 miRNA\uac00 \ubb34\uc5c7\uc778\uc9c0, \uadf8 \uae30\ub2a5\uacfc \uce58\ub8cc \uac00\ub2a5\uc131\uc5d0 \ub300\ud574 \uc54c\uc544\ubcf4\uace0, \uc6b0\ub9ac \uc5f0\uad6c\uc2e4\uc5d0\uc11c miRNA\ub97c \uc5b4\ub5bb\uac8c \ubd84\uc11d\ud558\ub294\uc9c0 \uc54c\uc544\ubcf4\uaca0\uc2b5\ub2c8\ub2e4.<\/span><\/p>\n

miRNA\ub780 \ubb34\uc5c7\uc778\uac00? \uae30\ub2a5\uacfc \uce58\ub8cc \uac00\ub2a5\uc131 <\/strong><\/h2>\n

miRNA\ub294 \uc77c\ubc18\uc801\uc73c\ub85c 20~24\uac1c\uc758 \ub274\ud074\ub808\uc624\ud2f0\ub4dc \uae38\uc774\ub97c \uac00\uc9c4 \uc791\uc740 \ub2e8\uc77c \uac00\ub2e5 RNA\uc774\uba70 \ub2e8\ubc31\uc9c8\uc744 \uc554\ud638\ud654\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. miRNA\ub294 \uc720\uc804\uc790 \ubc1c\ud604\uc744 \uc870\uc808\ud558\uc5ec \uc138\ud3ec \ub0b4\uc5d0\uc11c \uc5b4\ub5a4 \uc720\uc804\uc790\uac00 “\ud65c\uc131\ud654”\ub418\uace0 “\ud65c\uc131\ud654”\ub418\ub294\uc9c0\ub97c \uacb0\uc815\ud569\ub2c8\ub2e4. \uc774 \ud575\uc2ec \uae30\ub2a5\uc740 \uc815\uc0c1\uc801\uc778 \uc138\ud3ec \uc131\uc7a5, \ubd84\ud654, \uadf8\ub9ac\uace0 \uc138\ud3ec \uc0ac\uba78\uc744 \ud3ec\ud568\ud55c \uc138\ud3ec \uacfc\uc815\uc758 \uc870\uc808\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. <\/span><\/p>\n

\ub530\ub77c\uc11c \ud5a5\ud6c4 \uba87 \ub144 \ub3d9\uc548 miRNA\ub294 \ub2e4\uc591\ud55c \uc9c8\ubcd1\uc758 \ubc14\uc774\uc624\ub9c8\ucee4\ub85c\uc11c \ud070 \uc7a0\uc7ac\ub825\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc77c\ubd80 miRNA\ub294 \uc9c8\ubcd1 \ubc1c\uc0dd \ud6c4 \ud2b9\uc815 \uc218\uc900\uc73c\ub85c \ubc1c\ud604\ub418\ubbc0\ub85c, \uc774\ub7ec\ud55c miRNA\ub294 \uc870\uae30 \uc815\ubc00 \uc9c4\ub2e8 \ub9c8\ucee4\ub85c \ud65c\uc6a9\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc774\uc720\ub85c miRNA\ub294 \uc885\uc591\ud559\uc774\ub098 \uc2ec\ud608\uad00 \uc758\ud559\ucc98\ub7fc \uc870\uae30 \uc9c4\ub2e8\uc774 \ud544\uc218\uc801\uc778 \ubd84\uc57c\uc5d0\uc11c \uc7a0\uc7ac\uc801 \ubc14\uc774\uc624\ub9c8\ucee4\ub85c\uc11c \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud569\ub2c8\ub2e4. <\/span><\/p>\n

\uc720\uc804\uc790 \ubc14\uc774\uc624\ub9c8\ucee4 \uc678\uc5d0\ub3c4 miRNA \uce58\ub8cc\ubc95\uc740 \uc7a0\uc7ac\uc801\uc778 \uce58\ub8cc\uc801 \ud65c\uc6a9 \uac00\ub2a5\uc131\uc744 \ubaa8\uc0c9\ud574 \uc654\uc2b5\ub2c8\ub2e4. \uacfc\ud559\uc790\uc640 \uc5f0\uad6c\uc790\ub4e4\uc740 \ud2b9\uc815 miRNA\ub97c \ubaa8\ubc29\ud558\uac70\ub098 \uc5b5\uc81c\ud558\uc5ec \uc720\uc804\uc790 \ubc1c\ud604\uc744 \uc870\uc808\ud558\uace0 \uc554\uc774\ub098 \uc720\uc804 \uc9c8\ud658\uacfc \uac19\uc740 \uc9c8\ubcd1\uc744 \ud45c\uc801\uc73c\ub85c \uc0bc\ub294 \ubc29\ubc95\uc744 \uc5f0\uad6c\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc2e4\uc81c\ub85c C\ud615 \uac04\uc5fc\uacfc \uac19\uc740 \uc9c8\ud658\uc744 \uce58\ub8cc\ud558\uae30 \uc704\ud55c \uc784\uc0c1 \uc2dc\ud5d8\uc774 \uba87 \uac74 \ub4f1\ub85d<\/a> \ub418\uc5c8\uc2b5\ub2c8\ub2e4. <\/span><\/p>\n

\uc774 \ub178\ubca8\uc0c1\uc740 \uc774\ub7ec\ud55c \ubbf8\uc138 \ubd84\uc790\uc758 \uc911\uc694\uc131\uacfc \uc774\ub97c \ubc14\uc774\uc624\ub9c8\ucee4\ub85c \ud65c\uc6a9\ud558\uc5ec \uc870\uae30 \uc9c4\ub2e8 \ub3c4\uad6c\ub85c \ud65c\uc6a9\ud558\uace0, \uac1c\uc778 \ub9de\ucda4\ud615 \uce58\ub8cc \uc811\uadfc\ubc95\uc744 \ud601\uc2e0\ud560 \uc218 \uc788\ub294 \uc7a0\uc7ac\ub825\uc744 \uc81c\uc2dc\ud569\ub2c8\ub2e4. \ud604\uc7ac FDA \uc2b9\uc778\uc744 \ubc1b\uc740 miRNA \uae30\ubc18 \uc57d\ubb3c\uc740 \uc5c6\uc9c0\ub9cc, \uc774 \uc0c1\uc774 \uac00\uc838\uc624\ub294 \uad00\uc2ec\uacfc \uae30\uc220\uc758 \ubc1c\uc804\uc740 \uae0d\uc815\uc801\uc778 \ubbf8\ub798\ub97c \uc608\uace0\ud569\ub2c8\ub2e4. <\/span><\/p>\n

Kymos \uadf8\ub8f9\uacfc miRNA: \ud601\uc2e0\uc5d0 \ub300\ud55c \uc57d\uc18d<\/strong><\/h2>\n

miRNA\uc5d0 \ub300\ud55c \uc5f0\uad6c\uac00 \uc544\uc9c1 \ucd08\uae30 \ub2e8\uacc4\uc774\uace0 \uacfc\ud559\uacc4\uc5d0\uc11c\ub294 \uc5ec\uc804\ud788 \uc774 \ubd84\uc790\uc758 \uc7a0\uc7ac\ub825\uc744 \ud3c9\uac00\ud558\uace0 \uc788\uc5c8\uc9c0\ub9cc, \ub3c5\uc77c \uc0ac\uc774\ud2b8\uc5d0\uc11c\ub294 miRNA \uc5f0\uad6c\uac00 \ubbf8\ub798\uc5d0 \ubd84\uc790 \uc758\ud559\uc758 \uc911\uc2ec\uc774 \ub420 \uac83\uc774\ub77c\ub294 \uc0ac\uc2e4\uc744 \uc778\uc2dd\ud588\uc2b5\ub2c8\ub2e4.<\/span><\/p>\n

\ud575\uc0b0 \uc0dd\ubb3c\ubd84\uc11d\ud559\uacfc\uc758 \uacbd\ud5d8\uc744 \ud65c\uc6a9\ud558\uace0 \ub2e4\ub984\uc288\ud0c0\ud2b8 \uacf5\uacfc\ub300\ud559\uad50\uc640 \ub3c5\uc77c \uc815\ubd80\uc640\uc758 \ud611\ub825\uc744 \ud1b5\ud574 2016\ub144\ubd80\ud130 miRNA \uc815\ub7c9\ud654\ub97c \uc704\ud574 \ud2b9\ubcc4\ud788 \uc124\uacc4\ub41c \uc0dd\ubb3c\ubd84\uc11d\ubc95 \uac1c\ubc1c \ubc0f \uac80\uc99d\uc5d0 \ucc29\uc218\ud558\uc5ec, \ub2e4\ub978 \uc5f0\uad6c\uc790\ub4e4\ubcf4\ub2e4 \uc55e\uc11c \uc774 \ubd84\uc57c\uc758 \uc120\ub450\uc8fc\uc790\ub85c \uc790\ub9ac\ub9e4\uae40\ud588\uc2b5\ub2c8\ub2e4. \uc774 \uc5f0\uad6c\uc758 \uacb0\uc2e4\ub85c \ubc15\uc0ac \ud559\uc704\ub3c4 \ucde8\ub4dd\ud588\uc2b5\ub2c8\ub2e4. <\/span><\/p>\n

mRNA\uc640 miRNA \ubd84\uc11d\uc740 \ub9ce\uc740 \uc2e4\ud5d8\uc2e4\uc5d0\uc11c \uc218\ud589\ud560 \uc218 \uc788\uc9c0\ub9cc, \uacac\uace0\ud55c \uc815\ub7c9 \ubd84\uc11d\ubc95\uc744 \ud655\ub9bd\ud558\ub294 \uac83\uc740 \ud6e8\uc52c \uc5b4\ub835\uc2b5\ub2c8\ub2e4. \uc800\ud76c \ub3c5\uc77c \uc0ac\uc774\ud2b8\ub294 \uc6b0\uc218\uc2e4\ud5d8\uc2e4\uad00\ub9ac\uae30\uc900(GLP)\uc744 \uc900\uc218\ud558\uba70 \uc815\ud655\uc131\uacfc \uc7ac\ud604\uc131\uc744 \ubcf4\uc7a5\ud558\ub294 \uac80\uc99d\ub41c \ubd84\uc11d\ubc95\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. <\/span><\/p>\n

\uc774\ub7ec\ud55c \uc131\uacfc\ub294 \ub3c5\uc77c\uc758 \ud575\uc0b0 \ud300 \ub355\ubd84\uc5d0 \ubcf4\uc7a5\ub429\ub2c8\ub2e4. \uc774 \ud300\uc740 DNA\uc640 RNA\ub97c \ub2e4\ub8e8\ub294 \ub370 \uc218\ub144\uac04\uc758 \uacbd\ud5d8\uc744 \uac00\uc9c4 \uc804\ubb38\uac00\ub85c \uad6c\uc131\ub418\uc5b4 \uc788\uc73c\uba70, \ub2e4\uc591\ud55c \uc62c\ub9ac\uace0\ub274\ud074\ub808\uc624\ud2f0\ub4dc\uc5d0 \ub300\ud55c \ud45c\uc900\ud654\ub418\uace0 \uc7ac\ud604 \uac00\ub2a5\ud55c \ubc29\ubc95\uc744 \uac1c\ubc1c\ud558\uace0 \uac80\uc99d\ud558\ub294 \ub370 \uc8fc\ub825\ud574 \uc654\uc2b5\ub2c8\ub2e4.<\/span><\/p>\n

miRNA \uc815\ub7c9\ud654: RT-qPCR \uc804\ubb38\uac00 <\/strong><\/h2>\n

\uc55e\uc11c \uc0b4\ud3b4\ubcf8 \ubc14\uc640 \uac19\uc774, miRNA\ub97c \uc815\ud655\ud558\uac8c \uc815\ub7c9\ud654\ud558\ub824\uba74 \uc804\ubb38 \uacfc\ud559\uc790\ubfd0\ub9cc \uc544\ub2c8\ub77c \ucd5c\ucca8\ub2e8 \uae30\uc220\uacfc \uc7a5\ube44\ub3c4 \ud544\uc694\ud569\ub2c8\ub2e4. miRNA\ub294 \uc0dd\ubb3c\ud559\uc801 \uc2dc\ub8cc\uc5d0\uc11c \uadf9\ud788 \uc801\uc740 \uc591\uc73c\ub85c \uc874\uc7ac\ud558\uae30 \ub54c\ubb38\uc5d0, miRNA \uc218\uce58\uc758 \ubbf8\uc138\ud55c \ubcc0\ud654\uc870\ucc28\ub3c4 \uc9c8\ubcd1 \uc9c4\ub2e8\uc5d0 \uc911\uc694\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. <\/span><\/p>\n

\uc800\ud76c \ub3c5\uc77c \uc0ac\uc774\ud2b8\ub294 miRNA \ubd84\uc11d\uc5d0 \uc774\uc0c1\uc801\uc778 \uae30\uc220\uc778 \uc5ed\uc804\uc0ac \uc815\ub7c9 PCR(RT-qPCR)\uc744 \uc804\ubb38\uc73c\ub85c \ud569\ub2c8\ub2e4. \uc774 \uae30\uc220\uc740 \uadf9\uc18c\ub7c9\uc758 miRNA\ub97c \uc815\ub7c9\ud558\uace0 \uc815\ud655\ud558\uac8c \uce21\uc815\ud558\ub294 \ub370 \ud544\uc694\ud55c \uc815\ubc00\uc131, \ubbfc\uac10\ub3c4, \uadf8\ub9ac\uace0 \ud2b9\uc774\uc131\uc744 \uac16\ucd94\uace0 \uc788\uc2b5\ub2c8\ub2e4. <\/span><\/p>\n

RT-qPCR\uacfc \uc218\uc2ed \ub144\uac04 \ub300\ud615 \uc81c\uc57d \ud68c\uc0ac, \uc18c\uaddc\ubaa8 \ubc14\uc774\uc624\ud14c\ud06c \uae30\uc5c5, \uc720\uc804\uc790 \uce58\ub8cc \ud601\uc2e0 \uae30\uc5c5\uacfc \ud611\ub825\ud574 \uc628 \uacbd\ud5d8\uc744 \uacb0\ud569\ud558\uc5ec, \uc800\ud76c\uc758 \ubd84\uc11d\ubc95\uc740 \uacac\uace0\ud558\uace0 \uc2e0\ub8b0\ud560 \uc218 \uc788\uc73c\uba70 \uc784\uc0c1\uc801\uc73c\ub85c \uc801\ud569\ud569\ub2c8\ub2e4. Kymos Group\uc740 miRNA\ubfd0\ub9cc \uc544\ub2c8\ub77c mRNA, siRNA, \uc555\ud0c0\uba38, antagomiR, DNA \ub4f1 \ub2e4\ub978 \ud575\uc0b0 \ubd84\uc11d\uc744 \uc704\ud55c \ud575\uc0b0 \uc0dd\ubb3c\ubd84\uc11d\ubc95\uc744 \ucc98\uc74c\ubd80\ud130 \uac1c\ubc1c\ud558\uae30 \uc704\ud55c \ubd84\uc11d\ubc95 \uc774\uc804 \ubc0f \uae30\ucd08 R&D\uc5d0\ub3c4 \ub2a5\uc219\ud569\ub2c8\ub2e4. <\/span><\/p>\n

\uacb0\ub860<\/strong><\/h2>\n

miRNA \uc5f0\uad6c\uc758 \ubbf8\ub798\ub294 \ub9e4\uc6b0 \ud070 \uac00\ub2a5\uc131\uacfc \uc7a0\uc7ac\ub825\uc744 \uc9c0\ub2c8\uace0 \uc788\uc2b5\ub2c8\ub2e4. miRNA\uc5d0 \ub300\ud55c \uc9c0\uc2dd\uc774 \uc99d\uac00\ud568\uc5d0 \ub530\ub77c, miRNA \ubd84\uc790\ub97c \uc870\uae30 \uc9c4\ub2e8 \ubc0f \ud45c\uc801 \uce58\ub8cc\uc5d0 \uc801\uc6a9\ud560 \uac00\ub2a5\uc131\ub3c4 \ucee4\uc9c8 \uac83\uc785\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ubbf8\ub798 \uad00\uc810\uc5d0\uc11c, miRNA\ub294 \uc9c8\ubcd1\uc744 \uc870\uae30\uc5d0 \ubc1c\uacac\ud558\uace0, \uc9c8\ubcd1 \uc9c4\ud589\uc744 \ubaa8\ub2c8\ud130\ub9c1\ud558\uba70, \uac1c\uc778\uc758 \uc720\uc804\uc801 \ud2b9\uc131\uc5d0 \ub9de\ucd98 \ub9de\ucda4\ud615 \uce58\ub8cc\ub97c \ud1b5\ud574 \uadfc\ubcf8 \uc6d0\uc778\uc744 \uc9c1\uc811 \ud45c\uc801\uc73c\ub85c \uc0bc\uc544 \uc9c8\ubcd1\uc744 \uce58\ub8cc\ud558\ub294 \uc0c8\ub85c\uc6b4 \ubc29\ubc95\uc744 \uc81c\uacf5\ud560 \uc218 \uc788\uc744 \uac83\uc785\ub2c8\ub2e4. <\/span><\/p>\n

Kymos \uadf8\ub8f9, \ud2b9\ud788 \ub3c5\uc77c \uc9c0\uc0ac\uac00 \uc774\uc804\uc5d0\ub294 \ub2f9\uc5f0\ud558\uac8c \uc5ec\uaca8\uc84c\ub358 \uc774 \ubd84\uc790\uc758 \uc131\uacf5\uc5d0 \uae30\uc5ec\ud574 \uc654\ub2e4\ub294 \uc810\uc744 \uc790\ub791\uc2a4\ub7fd\uac8c \uc0dd\uac01\ud569\ub2c8\ub2e4. \uacfc\ud559\uc801 \ubc1c\uc804\uc744 \uc55e\uc11c \uc608\uce21\ud574 \uc628 \uc5ed\uc0ac\uc640 \uacfc\ud559\uc801 \ubc1c\uacac\uacfc \uc784\uc0c1 \uc801\uc6a9 \uc0ac\uc774\uc758 \uac04\uadf9\uc744 \uba54\uc6b0\ub824\ub294 \ud5cc\uc2e0\uc744 \ubc14\ud0d5\uc73c\ub85c, \uc800\ud76c\ub294 miRNA \ubc0f RNA \ubd84\uc57c\uc758 \ucc28\uc138\ub300 \ubc1c\uc804\uc744 \uc9c0\uc6d0\ud560 \uc900\ube44\uac00 \ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4. <\/span><\/p>\n

\ub9c8\uc9c0\ub9c9\uc73c\ub85c \ub178\ubca8\uc0c1\uc744 \uc218\uc0c1\ud55c \ube45\ud130 \uc554\ube0c\ub85c\uc2a4\uc640 \uac8c\ub9ac \ub8e8\ube0c\ucfe4\uc5d0\uac8c \ucd95\ud558\ub97c \uc804\ud569\ub2c8\ub2e4. \uc774 \uc0c1\uc740 \ub450 \ubd84\uc758 \uc5c5\uc801\uacfc miRNA\uc758 \uc911\uc694\uc131\uc774 \uc778\uc815\ubc1b\uc740 \uac83\uc785\ub2c8\ub2e4.<\/span><\/p>\n

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