{"id":27305,"date":"2019-12-10T11:07:09","date_gmt":"2019-12-10T10:07:09","guid":{"rendered":"https:\/\/kymos.com\/news\/lluisa-garcia-%eb%b0%95%ec%82%ac%eb%8a%94-%ec%82%ac%eb%a5%b4%ed%83%84%ec%9d%98-n-%eb%8b%88%ed%8a%b8%eb%a1%9c%ec%82%ac%eb%af%bc-%eb%b6%88%ec%88%9c%eb%ac%bc%ec%9d%84-%ea%b4%80%eb%a6%ac%ed%95%98%eb%8a%94\/"},"modified":"2019-12-10T11:07:09","modified_gmt":"2019-12-10T10:07:09","slug":"lluisa-garcia-%eb%b0%95%ec%82%ac%eb%8a%94-%ec%82%ac%eb%a5%b4%ed%83%84%ec%9d%98-n-%eb%8b%88%ed%8a%b8%eb%a1%9c%ec%82%ac%eb%af%bc-%eb%b6%88%ec%88%9c%eb%ac%bc%ec%9d%84-%ea%b4%80%eb%a6%ac%ed%95%98%eb%8a%94","status":"publish","type":"post","link":"https:\/\/kymos.com\/ko\/news\/lluisa-garcia-%eb%b0%95%ec%82%ac%eb%8a%94-%ec%82%ac%eb%a5%b4%ed%83%84%ec%9d%98-n-%eb%8b%88%ed%8a%b8%eb%a1%9c%ec%82%ac%eb%af%bc-%eb%b6%88%ec%88%9c%eb%ac%bc%ec%9d%84-%ea%b4%80%eb%a6%ac%ed%95%98%eb%8a%94\/","title":{"rendered":"Llu\u00efsa Garcia \ubc15\uc0ac\ub294 \uc0ac\ub974\ud0c4\uc758 N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc \ubd88\uc21c\ubb3c\uc744 \uad00\ub9ac\ud558\ub294 \ubc29\ubc95\uc5d0 \ub300\ud574 \uc870\uc5b8\ud569\ub2c8\ub2e4."},"content":{"rendered":"

“\uc720\uc5f0\ud55c \ubd84\uc11d CRO\uc640 \uc644\uc804\ud55c \uc704\ud5d8 \ud3c9\uac00\ub97c \ud1b5\ud574 \ub2c8\ud2b8\ub85c\uc0ac\ubbfc \ubd88\ud655\uc2e4\uc131\uc5d0 \ub300\ucc98\ud558\uc138\uc694”<\/em><\/span><\/h3>\n
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Llu\u00efsa Garc\u00eda \ubc15\uc0ac, Kymos Pharma Services<\/strong><\/span><\/p>\n

\uc0ac\ub974\ud0c4\uc73c\ub85c \uc54c\ub824\uc9c4 \ud608\uc555\uc57d\uc5d0\uc11c N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc \ubd88\uc21c\ubb3c\uc774 \ubc1c\uacac\ub418\uba74\uc11c \ub9ce\uc740 \uad00\uc2ec\uc774 \uc9d1\uc911\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc774 \ubb38\uc81c\uac00 \uc5b4\ub5bb\uac8c \ubc1c\uc0dd\ud588\ub294\uc9c0 \uc124\uba85\ud558\uace0, KYMOS\uc758 \uacf5\ub3d9 \ucc3d\ub9bd\uc790 \uacb8 \ucd5c\uace0\uc6b4\uc601\ucc45\uc784\uc790(COO)\uc774\uc790 \uc720\uae30\ud654\ud559 \ubc15\uc0ac\uc778 \uc800\ud76c \uc804\ubb38\uac00 \ub8e8\uc774\uc0ac \uac00\ub974\uc2dc\uc544 \ubc15\uc0ac\ub97c \ub9cc\ub098 \ud604\uc7ac\uc758 \uc6b0\ub824 \uc0ac\ud56d\uacfc \ud574\uacb0 \ubc29\uc548\uc5d0 \ub300\ud574 \uc774\uc57c\uae30\ub97c \ub098\ub220\ubd05\ub2c8\ub2e4. <\/span><\/p>\n

“\uc800\ud76c\ub294 \uc804 \uc138\uacc4\uc801\uc778 \uc5b4\ub824\uc6c0\uc5d0 \uc9c1\uba74\ud574 \uc788\uc9c0\ub9cc, KYMOS\ub294 \uc0dd\ubb3c\uc758\uc57d\ud488 \uc2dc\uc7a5\uc758 \uac11\uc791\uc2a4\ub7fd\uace0 \uc608\uc0c1\uce58 \ubabb\ud55c \uc694\uad6c\uc5d0 \ub300\uc751\ud558\uae30 \uc704\ud574 \uc0c8\ub85c\uc6b4 \ubd84\uc11d\ubc95, \uc11c\ube44\uc2a4 \ubd80\uc11c, \uc2ec\uc9c0\uc5b4\ub294 \uc804\uccb4 \ubd80\uc11c\ub97c \uac1c\ubc1c\ud574 \uc628 \uc5ed\uc0ac\ub97c \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4.”\ub77c\uace0<\/em> \uac00\ub974\uc2dc\uc544 \ubc15\uc0ac\ub294 \ub9d0\uc744 \uc2dc\uc791\ud588\uc2b5\ub2c8\ub2e4. “CRO\ub85c\uc11c \uc800\ud76c\uc758 \uc784\ubb34\ub294 \ucd5c\uc2e0 \uc0c1\ud669\uc744 \ud30c\uc545\ud558\ub294 \uac83\uc774\uba70, \ub2e4\ud589\ud788 \uc800\ud76c\ub294 APCI \uc18c\uc2a4\ub97c \uc774\uc6a9\ud55c LC-MS\/MS \ubc0f HS-GC\/MS \ubd84\uc11d \ubd84\uc57c\uc5d0\uc11c 20\ub144\uac04\uc758 \uc0ac\ub0b4 \uacbd\ud5d8\uc744 \ubcf4\uc720\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ub450 \ubd84\uc11d \ubaa8\ub450 EMA\uc640 FDA\uc5d0\uc11c \ub2c8\ud2b8\ub85c\uc0ac\ubbfc \uc815\ub7c9 \ubd84\uc11d\uc744 \uc704\ud574 \uad8c\uc7a5\ud558\ub294 \ubd84\uc11d\ubc95\uc785\ub2c8\ub2e4.”<\/em> <\/span><\/p>\n

N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc \ubd88\uc21c\ubb3c\uc758 \ubc30\uacbd<\/strong><\/span>
\n2018\ub144 6\uc6d4, ‘\uc0ac\ub974\ud0c4’\uc73c\ub85c \uc54c\ub824\uc9c4 \ud608\uc555\uc57d\uc5d0\uc11c \uc5ec\ub7ec N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc \ubd88\uc21c\ubb3c\uc774 \uac80\ucd9c\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ucd5c\uadfc\uc5d0\ub294 \uc704\uada4\uc591 \uce58\ub8cc\uc81c\uc778 \ub77c\ub2c8\ud2f0\ub518\uacfc \ub2e4\ub978 \uc57d\ubb3c\uc5d0\uc11c\ub3c4 N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc \ubd88\uc21c\ubb3c\uc774 \uac80\ucd9c\ub418\uc5c8\uc2b5\ub2c8\ub2e4. N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc\uc740 \uc778\uccb4 \ubc1c\uc554 \uac00\ub2a5\uc131\uc774 \uc788\ub294 \ubb3c\uc9c8\ub85c \ubd84\ub958\ub418\uc5b4 \uc2ec\uac01\ud55c \uac74\uac15 \uc704\ud5d8\uc744 \ucd08\ub798\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub2e4\uc591\ud55c \uc758\uc57d\ud488\uc5d0\uc11c \uc0c8\ub85c\uc6b4 \ub2c8\ud2b8\ub85c\uc0ac\ubbfc\uc774 \uac80\ucd9c\ub418\ub294 \uc0ac\ub840\uac00 \uc99d\uac00\ud568\uc5d0 \ub530\ub77c, EMA\ub294 \uc9c0\ub09c 9\uc6d4 \ubaa8\ub4e0 \uc81c\uc57d \ud68c\uc0ac\uc5d0 \uc790\uc0ac\uc5d0\uc11c \uc81c\uc870\ub41c \uc758\uc57d\ud488 \ubc0f \ud65c\uc131 \uc131\ubd84(API)\uc5d0 \uc5b4\ub5a4 \ub2c8\ud2b8\ub85c\uc0ac\ubbfc \ubd88\uc21c\ubb3c\uc774 \uac80\ucd9c\ub420 \uac00\ub2a5\uc131\uc774 \ub192\uc740\uc9c0 \ud30c\uc545\ud558\uae30 \uc704\ud55c \uc704\ud574\uc131 \ud3c9\uac00\ub97c \uc2e4\uc2dc\ud558\uace0, \ubaa8\ub4e0 \uc704\ud5d8 \uc81c\ud488\uc5d0\uc11c \ud574\ub2f9 \ubd88\uc21c\ubb3c\uc758 \uc874\uc7ac \uc5ec\ubd80\ub97c \uc2e4\ud5d8\uc801\uc73c\ub85c \ud3c9\uac00\ud560 \uac83\uc744 \uc694\uccad\ud588\uc2b5\ub2c8\ub2e4. <\/span><\/p>\n

\uac00\ub974\uc2dc\uc544 \ubc15\uc0ac\ub294 “\uc774 \ubb38\uc81c\ub294 \uc5ec\ub7ec \uac00\uc9c0 \uc774\uc720\ub85c \ub9e4\uc6b0 \ubcf5\uc7a1\ud569\ub2c8\ub2e4.”\ub77c\uace0 \uc8fc\uc7a5\ud569\ub2c8\ub2e4. “\uc6b0\uc120, \uaddc\uc81c \uc694\uac74\uc740 \ud654\ud559\uc801\uc73c\ub85c \ud569\uc131\ub41c API\ub97c \ud3ec\ud568\ud558\ub294 \ubaa8\ub4e0 \uc778\uccb4 \uc758\uc57d\ud488\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce69\ub2c8\ub2e4. \uc774 API\ub294 \uace0\uc720\ud55c \ub2e4\uc591\uc131, \ubcf5\uc7a1\ud55c \ud569\uc131 \uacbd\ub85c, \ub2c8\ud2b8\ub85c\uc0ac\ubbfc \ubd88\uc21c\ubb3c(\ubd80\ud615\uc81c \ubc0f \uc6a9\ub9e4 \ud3ec\ud568)\uc758 \uc7a0\uc7ac\uc801 \uacf5\uae09\uc6d0, \uadf8\ub9ac\uace0 \uad50\ucc28 \uc624\uc5fc \uc5ed\ud559\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uac8c\ub2e4\uac00 EU \ub2f9\uad6d\uc740 2020\ub144 3\uc6d4\uae4c\uc9c0 \uc704\ud5d8 \ud3c9\uac00 \uacb0\uacfc\ub97c \ubcf4\uace0\ud574 \ub2ec\ub77c\uace0 \uc694\uccad\ud588\uc2b5\ub2c8\ub2e4. \uc774\ud6c4 \uae30\uc5c5\ub4e4\uc740 \ucd5c\ub300 3\ub144 \ub3d9\uc548 \ubaa8\ub4e0 \uc81c\uc870 \ubc0f \uc2dc\ud5d8 \uccb4\uacc4\ub97c \uc870\uc815\ud558\uc5ec \ucd5c\uc885\uc801\uc73c\ub85c \uc81c\ud488\uc5d0 \ub2c8\ud2b8\ub85c\uc0ac\ubbfc\uc774 \uc815\ub7c9\ud654 \uac00\ub2a5\ud55c \uc218\uc900\uc73c\ub85c \uc874\uc7ac\ud558\uc9c0 \uc54a\ub294\ub2e4\ub294 \uac83\uc744 \ubcf4\uc7a5\ud574\uc57c \ud569\ub2c8\ub2e4.<\/x> EU\uc5d0\uc11c \uc0ac\uc6a9\ud558\uae30 \uc804\uc5d0 0.03ppm(0.03ppm)\uc744 \ucd08\uacfc\ud574\uc11c\ub294 \uc548 \ub429\ub2c8\ub2e4. \uc720\uae30\ud654\ud559\uc790\ub77c\uba74 \ub204\uad6c\ub098 \uc54c\uaca0\uc9c0\ub9cc, \uc774\ub294 \ub9e4\uc6b0 \uc9e7\uc740 \uc2dc\uac04\uc5d0 \ub2ec\uc131\ud558\uae30\uc5d0\ub294 \ub108\ubb34 \ub9ce\uc740 \uc591\uc785\ub2c8\ub2e4. <\/em><\/span><\/p>\n

N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc \ubd88\uc21c\ubb3c \uad00\ub9ac <\/strong><\/span>
\n“\uc800\ud76c \uae00\ub85c\ubc8c \uace0\uac1d\ub4e4\uc740 \ub2e4\uc591\ud55c \uc694\uad6c \uc0ac\ud56d\uc744 \uac00\uc9c0\uace0 KYMOS\uc5d0 \uc811\uadfc\ud569\ub2c8\ub2e4.”<\/em> \ub77c\uace0 \uac00\ub974\uc2dc\uc544 \ubc15\uc0ac\ub294 \uc124\uba85\ud569\ub2c8\ub2e4. “\ud2b9\uc815 N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc \ubd88\uc21c\ubb3c, \ud2b9\ud788 \uc6d0\ub8cc\uc758\uc57d\ud488(API) \uac80\uc0ac \uc694\uccad\ubd80\ud130 \ub2e4\uc591\ud55c \uc2dc\ud310 \uc758\uc57d\ud488\uc5d0\uc11c \uc218\uc2ed \uac00\uc9c0 \ub2c8\ud2b8\ub85c\uc0ac\ubbfc\uc744 \uac80\ucd9c\ud558\uae30 \uc704\ud55c \ub354\uc6b1 \uc57c\uc2ec\ucc2c \uc2a4\ud06c\ub9ac\ub2dd \ud504\ub85c\uc81d\ud2b8\uae4c\uc9c0 \ub2e4\uc591\ud569\ub2c8\ub2e4. \uc800\ud76c \uace0\uac1d \uc911 \uc77c\ubd80\ub294 2017\ub144 \uc720\ub7fd\uc758\uc57d\ud488\uccad(EMA)\uc774 \uc758\uc57d\ud488\uc758 \uae08\uc18d \ud568\ub7c9 \uc81c\ud55c\uc744 \uc704\ud55c ICH Q3D \uc9c0\uce68\uc744 \ubc1c\ud45c\ud588\uc744 \ub54c\ubd80\ud130 \ub3d9\uc77c\ud55c \uc804\ub7b5\uc744 \ub530\ub974\ub294 \uac83 \uac19\uc2b5\ub2c8\ub2e4.”\ub77c\uace0<\/g> \ub8e8\uc774\uc0ac\ub294 \ud68c\uc0c1\ud569\ub2c8\ub2e4. “\ub2f9\uc2dc KYMOS\ub294 \ud604\uc7ac\uc758 \uc6d0\uc18c \ubd88\uc21c\ubb3c \ubd80\uc11c\uc5d0 \uc0c8\ub85c\uc6b4 ICP\/MS \uc7a5\ube44\ub97c \ub3c4\uc785\ud558\ub294 \ub4f1 \uc774\ub7ec\ud55c \uacfc\uc81c\ub97c \uc131\uacf5\uc801\uc73c\ub85c \uc218\ud589\ud588\uc2b5\ub2c8\ub2e4. 2\ub144 \uc804\uc5d0\ub294 \uc798 \ud2b9\uc131\ud654\ub41c \uae08\uc18d \ubd88\uc21c\ubb3c 24\uac1c\ub9cc \ucc98\ub9ac\ud558\uba74 \ub410\uc2b5\ub2c8\ub2e4. \uc9c0\uae08\uc740 \ub2c8\ud2b8\ub85c\uc0ac\ubbfc \ubaa9\ub85d\uc774 \ud6e8\uc52c \uae38\uace0 \uba85\ud655\ud55c \uae30\uc900\ub3c4 \ubd80\uc871\ud558\uae30 \ub54c\ubb38\uc5d0 \uc77c\ubc18\uc801\uc778 \ubd84\uc11d\ubc95\uc73c\ub85c\ub294 \ucda9\ubd84\ud788 \ud3ec\uad04\uc801\uc778 \uacb0\uacfc\ub97c \uc5bb\uae30 \uc5b4\ub824\uc6b8 \uc218 \uc788\uc2b5\ub2c8\ub2e4.”\ub77c\uace0<\/em> \uadf8\ub140\ub294 \ub367\ubd99\uc785\ub2c8\ub2e4. <\/span><\/p>\n

“\uc131\uacf5\uc801\uc778 N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc \uc804\ub7b5\uc758 \ud575\uc2ec\uc740 AZIERTA<\/a> \uc640 \uac19\uc740 \ud30c\ud2b8\ub108\uac00 \uc81c\uacf5\ud558\ub294 \uac83\uacfc \uac19\uc740 \uc644\uc804\ud55c \uc704\ud5d8 \ud3c9\uac00\ub97c \ud1b5\ud574 \uc7a0\uc7ac\uc801\uc778 \ub2c8\ud2b8\ub85c\uc0ac\ubbfc\uc744 \ucc3e\uc544\ub0b4\uace0 \uc774\ub97c \uc720\uc5f0\ud55c \ubd84\uc11d \uc811\uadfc \ubc29\uc2dd\uacfc \uacb0\ud569\ud558\ub294 \uac83\uc785\ub2c8\ub2e4. \uc7ac\ud3c9\uac00 \uacb0\uacfc\uac00 \ubd88\ud655\uc2e4\ud55c \uacbd\uc6b0 \uc0c8\ub85c\uc6b4 \ubb3c\uc9c8\uacfc \ubd88\uc21c\ubb3c\uc5d0 \ub300\ud55c \uac80\ucd9c \ubc29\ubc95\uc744 \uc2e0\uc18d\ud558\uac8c \uc870\uc815\ud560 \uc218 \uc788\ub294 \ucda9\ubd84\ud55c \uc804\ubb38 \uc9c0\uc2dd\uc744 \uac16\ucd98 CRO\uc640 \ud611\ub825\ud558\uc2ed\uc2dc\uc624.”<\/em><\/span><\/p>\n

N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc \ubd88\uc21c\ubb3c \uac80\ucd9c\uc758 \ud2b9\ubcc4\ud55c \uc810\uc740 \ubb34\uc5c7\uc785\ub2c8\uae4c?<\/strong><\/span>
\nKYMOS\ub294 \ubc14\ub974\uc140\ub85c\ub098\uc5d0 \uc788\ub294 \uc0dd\ubb3c\ubd84\uc11d \uc5f0\uad6c\uc2e4\uacfc \uc774\ud0c8\ub9ac\uc544 \uc790\ud68c\uc0ac\uc778 Pharmaprogress\uc5d0\uc11c \ucd5c\uc2e0 \uc138\ub300 LC-MS\/MS \ubc0f HS-GC\/MS \uc7a5\ube44\ub97c \ud65c\uc6a9\ud574 \ubd88\uc21c\ubb3c \uac80\ucd9c\uc744 \uc704\ud55c \uace0\uac10\ub3c4, \uace0\ud2b9\uc774\uc131 \ubc29\ubc95\uc744 \uac1c\ubc1c\ud558\uace0 \uac80\uc99d\ud558\ub294 \ub370 \uc218\ub144\uac04\uc758 \uacbd\ud5d8\uc744 \uc313\uc558\uc2b5\ub2c8\ub2e4.<\/span><\/p>\n

\uac00\ub974\uc2dc\uc544 \ubc15\uc0ac \ub294 “\ud718\ubc1c\uc131 \ubb3c\uc9c8\uc5d0\uc11c \uc720\uc804\ub3c5\uc131 \ubd88\uc21c\ubb3c\uc5d0 \uc774\ub974\uae30\uae4c\uc9c0 \ubaa8\ub4e0 \uc885\ub958\uc758 \ubb3c\uc9c8\uc744 \ud2b9\uc131\ud654\ud560 \uc218 \uc788\ub294 \ub178\ud558\uc6b0\uc640 \uc644\ubcbd\ud558\uac8c \uac16\ucdb0\uc9c4 \ub450 \uac1c\uc758 \ubcc4\ub3c4 \uc2dc\uc124\uc744 \uac16\ucd94\uace0 \uc788\uae30 \ub54c\ubb38\uc5d0 \uae30\ub85d\uc801\uc778 \uc2dc\uac04 \uc548\uc5d0 \uc5b4\ub824\uc6b4 \ud504\ub85c\uc81d\ud2b8\uc5d0 \ub300\ucc98\ud560 \uc218 \uc788\ub294 \uc5ed\ub7c9\uc744 \uac16\ucd94\uace0 \uc788\uc2b5\ub2c8\ub2e4.”<\/em> \ub77c\uace0 \uc124\uba85\ud588\uc2b5\ub2c8\ub2e4.<\/span><\/p>\n

KYMOS\ub294 \uc5b4\ub5bb\uac8c \ub3c4\uc6c0\uc744 \uc904 \uc218 \uc788\ub098\uc694?<\/strong><\/span>
\n\uc778\uccb4 \uc758\uc57d\ud488\uc758 N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc \uc624\uc5fc\uc744 \ubc29\uc9c0\ud558\uae30 \uc704\ud55c \ud604\ud589 \uc9c0\uce68\uc740 N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc \uc0dd\uc131 \uc704\ud5d8\uc774 \uc788\ub294 \uac83\uc73c\ub85c \ud655\uc778\ub41c \uc758\uc57d\ud488 \ubc0f API\uc5d0 \ub300\ud55c \ucd08\uae30 \uc704\ud5d8 \ud3c9\uac00\uc640 \ucd94\uac00 \ud655\uc778 \uc2dc\ud5d8\uc744 \ubcd1\ud589\ud569\ub2c8\ub2e4. KYMOS\ub294 \uc774 \ud655\uc778 \ub2e8\uacc4\uc5d0 \ub300\ud574 \uad11\ubc94\uc704 \ub610\ub294 \ud2b9\uc815 \ub450 \uac00\uc9c0 \ub300\uc548\uc801 \uc811\uadfc \ubc29\uc2dd\uc744 \uc81c\uc548\ud569\ub2c8\ub2e4. <\/span><\/p>\n

\uac00\ub974\uc2dc\uc544 \ubc15\uc0ac\ub294 “\uc77c\ubd80 \uace0\uac1d\uc740 \uc704\ud574\uc131 \ud3c9\uac00\uc5d0\uc11c \ud655\uc778\ub41c \ub2c8\ud2b8\ub85c\uc0ac\ubbfc\uc5d0 \ub300\ud55c \uad6c\uccb4\uc801\uc778 \ubd84\uc11d\ubc95 \uac1c\ubc1c \ubc0f \uac80\uc99d\uc744 \uc694\uccad\ud569\ub2c8\ub2e4.”<\/em> \ub77c\uace0 \ub9d0\ud558\uba70, “\ub2e4\ub978 \uace0\uac1d\ub4e4\uc740 \ubcf4\ub2e4 \uc2ec\uce35\uc801\uc778 \uc815\ub7c9 \ubd84\uc11d\uc5d0 \uc55e\uc11c \uac00\uc7a5 \ud754\ud55c \ub2c8\ud2b8\ub85c\uc0ac\ubbfc\uc5d0 \ub300\ud55c \ubcf4\ub2e4 \uc77c\ubc18\uc801\uc778 \uc2a4\ud06c\ub9ac\ub2dd\uc744 \uc120\ud638\ud569\ub2c8\ub2e4. \ud604\uc7ac \uc800\ud76c \ubd84\uc11d\ubc95\uc740 7~12\uc885\uc758 N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc\uc744 \ud3ec\ud568\ud558\uace0 \uc788\uc73c\uba70, \uac01 \uc0ac\ub840\uc5d0 \ub530\ub77c \ub450 \uac00\uc9c0 \ub2e4\ub978 \ubd84\uc11d \uae30\ubc95\uc744 \uc0ac\uc6a9\ud558\uc9c0\ub9cc, \ud56d\uc0c1 \uc815\ub7c9\ud654 \uaddc\uc81c \uae30\uc900\uc744 \uc900\uc218\ud558\uace0 \uc788\uc73c\uba70, 2\ub144 \ud6c4\uc5d0\ub294 0.03ppm \ubbf8\ub9cc\uc73c\ub85c \uc81c\ud55c\ub420 \uc608\uc815\uc785\ub2c8\ub2e4.”\ub77c\uace0 \ub367\ubd99\uc600\uc2b5\ub2c8\ub2e4.<\/em> <\/span><\/p>\n

N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc\uc758 \ubbf8\ub798<\/strong><\/span>
\n\uc778\uac04 \uc758\uc57d\ud488\uc5d0\uc11c \ub2c8\ud2b8\ub85c\uc0ac\ubbfc \uac80\ucd9c\uc758 \ubbf8\ub798\uc5d0 \ub300\ud55c \uc9c8\ubb38\uc5d0 \uac00\ub974\uc2dc\uc544 \ubc15\uc0ac\ub294 \ucd5c\ub300 \uc791\uc5c5\ub7c9\uc740 \uc544\uc9c1 \uc624\uc9c0 \uc54a\uc558\ub2e4\uace0 \ud655\uc2e0\ud588\uc2b5\ub2c8\ub2e4.<\/span><\/p>\n

\uadf8\ub140\ub294 “\uace0\uac1d\ub4e4 \uc0ac\uc774\uc5d0\ub294 \ubd80\uc778\ud560 \uc218 \uc5c6\uc744 \ub9cc\ud07c \ub9ce\uc740 \ubd88\uc548\uac10\uc774 \uc788\uc9c0\ub9cc, \uadf8\ub4e4 \uc911 \ub2e4\uc218\ub294 \uc774\uc81c \ub9c9 \uc704\ud5d8 \ud3c9\uac00\ub97c \uc900\ube44\ud558\uae30 \uc2dc\uc791\ud55c \ub2e8\uacc4\uc785\ub2c8\ub2e4.”<\/em> \ub77c\uace0 \uc8fc\uc7a5\ud569\ub2c8\ub2e4.<\/span><\/p>\n

“\ubaa8\ub4e0 \ud3c9\uac00\ub294 \ub2a6\uc5b4\ub3c4 2020\ub144 3\uc6d4 26\uc77c\uae4c\uc9c0 \uc644\ub8cc\ud558\uace0 \ubcf4\uace0\ud574\uc57c \ud558\ubbc0\ub85c \ub0b4\ub144 \ubd04\uc5d0 \uc218\uc694\uac00 \uae09\uc99d\ud560 \uac00\ub2a5\uc131\uc774 \ud06c\uc9c0\ub9cc, \ub9c8\uac10\uc77c\uc774 \ucd09\ubc15\ud55c \ub9cc\ud07c \uc720\uc608 \uae30\uac04\uc744 \ub450\ub294 \uac83\ub3c4 \ubd88\uac00\ub2a5\ud55c \uc77c\uc740 \uc544\ub2d9\ub2c8\ub2e4.” <\/em><\/span><\/p>\n

KYMOS\uac00 \uc774\uc804\uc5d0 \uc6d0\uc18c \ubd88\uc21c\ubb3c\uc5d0 \ub300\ud574 \uacbd\ud5d8\ud55c \ubc14\ub97c \ub3cc\uc774\ucf1c\ubcf4\uba74, \uac00\ub974\uc2dc\uc544 \ubc15\uc0ac\ub294 \ube44\uc2b7\ud55c \uc9c4\ud654\uac00 \uc788\uc744 \uac83\uc73c\ub85c \uc608\uc0c1\ud569\ub2c8\ub2e4.<\/span><\/p>\n

\ubcf4\uac74 \ub2f9\uad6d\uc774 \ud310\ub9e4 \ud5c8\uac00 \uc18c\uc9c0\uc790\ub85c\ubd80\ud130 \uccab \ubc88\uc9f8 \uc704\ud574\uc131 \ud3c9\uac00\ub97c \ubc1b\uc73c\uba74 \uc704\ud5d8 \uc81c\ud488, \ub2c8\ud2b8\ub85c\uc0ac\ubbfc \uc624\uc5fc\uc758 \uc7a0\uc7ac\uc801 \uc6d0\uc778, \uadf8\ub9ac\uace0 \uad8c\uc7a5 \uc608\ubc29 \uc870\uce58\uc5d0 \ub300\ud55c \ub354\uc6b1 \uba85\ud655\ud55c \uc9c0\uce68\uc744 \uae30\ub300\ud574\uc57c \ud569\ub2c8\ub2e4. \uc6d0\uc18c \ubd88\uc21c\ubb3c\uc5d0 \ub300\ud55c ICH Q3D \uc9c0\uce68 \ub610\ud55c \ud65c\ub3d9 \uae09\uc99d\uc744 \ucd09\ubc1c\ud588\uc9c0\ub9cc, 2\ub144 \ud6c4 \uc0c1\ud669\uc740 \ubd84\uba85\ud788 \uc548\uc815\ub418\uc5c8\uc2b5\ub2c8\ub2e4. N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc\uc740 \uae08\uc18d \ubd88\uc21c\ubb3c\ubcf4\ub2e4 \ud6e8\uc52c \ub354 \uc2ec\uac01\ud558\uace0 \uad11\ubc94\uc704\ud55c \uc601\ud5a5\uc744 \ubbf8\uce58\uae30 \ub54c\ubb38\uc5d0 \uc774\ub7ec\ud55c \uc0c1\ud669\uc774 \ub354 \uc624\ub798 \uc9c0\uc18d\ub420 \uc218 \uc788\ub2e4\uace0 \uc8fc\uc7a5\ud560 \uc218\ub3c4 \uc788\uc2b5\ub2c8\ub2e4. <\/em><\/span><\/p>\n

\uc774 \uc2dc\uc810\uc5d0\uc11c \uac00\ub974\uc2dc\uc544 \ubc15\uc0ac\ub294 \uc704\uc548\uc774 \ub418\ub294 \uc0dd\uac01\uc73c\ub85c \uacb0\ub860\uc744 \ub0b4\ub9bd\ub2c8\ub2e4.<\/span><\/p>\n

\ud55c \uac00\uc9c0\ub294 \ubd84\uba85\ud569\ub2c8\ub2e4. KYMOS\ub294 \uad00\ub828 \ubd84\uc11d \ubc29\ubc95\uc5d0 \ub300\ud55c \ud48d\ubd80\ud55c \uc0ac\ub0b4 \uacbd\ud5d8\uc744 \ubcf4\uc720\ud558\uace0 \uc788\uc73c\uba70, \ucd5c\uace0\uae09 LC-MS\/MS \ubc0f HS-GC\/MS \uc7a5\ube44\ub97c \uc644\ubcbd\ud558\uac8c \uac16\ucd94\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ubb34\uc5c7\ubcf4\ub2e4\ub3c4 \ubd88\uc21c\ubb3c \uac80\ucd9c \ubc29\ubc95\uc758 \uac80\uc99d \ubc0f \uac1c\ubc1c\uc5d0 \ub2a5\uc219\ud569\ub2c8\ub2e4. \ub530\ub77c\uc11c \ubbf8\ub798\uac00 \uc5b4\ub5bb\uac8c \uc804\uac1c\ub418\ub4e0, \uc800\ud76c\ub294 \ucda9\uc131 \uace0\uac1d\ub4e4\uacfc \ud568\uaed8 \ub2c8\ud2b8\ub85c\uc0ac\ubbfc \uc0ac\ud0dc\ub97c \ud5e4\uccd0\ub098\uac08 \uac83\uc774\ub77c\uace0 \ud655\uc2e0\ud569\ub2c8\ub2e4.<\/em><\/span><\/p>\n

N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc \uac80\uc0ac \uc11c\ube44\uc2a4<\/a> \uc5d0 \ub300\ud55c \uc790\uc138\ud55c \ub0b4\uc6a9\uc740 \ub2f9\uc0ac \uc6f9\uc0ac\uc774\ud2b8\uc5d0\uc11c \ud655\uc778\ud558\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

“\uc720\uc5f0\ud55c \ubd84\uc11d CRO\uc640 \uc644\uc804\ud55c \uc704\ud5d8 \ud3c9\uac00\ub97c \ud1b5\ud574 \ub2c8\ud2b8\ub85c\uc0ac\ubbfc \ubd88\ud655\uc2e4\uc131\uc5d0 \ub300\ucc98\ud558\uc138\uc694” […]<\/p>\n","protected":false},"author":6,"featured_media":27308,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[259,261],"tags":[],"class_list":["post-27305","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-259","category-261"],"acf":[],"yoast_head":"\n\ud1b5\ucc30\ub825\uc0ac\ub974\ud0c4\uc758 N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc \ubd88\uc21c\ubb3c\uc744 \uad00\ub9ac\ud558\ub294 \ubc29\ubc95<\/title>\n<meta name=\"description\" content=\"\uc0ac\ub974\ud0c4\uc73c\ub85c \uc54c\ub824\uc9c4 \ud608\uc555\uc57d\uc5d0\uc11c N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc \ubd88\uc21c\ubb3c\uc774 \ubc1c\uacac\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ub8e8\uc774\uc0ac \uac00\ub974\uc2dc\uc544 \ubc15\uc0ac\uac00 \uc790\uc2e0\uc758 \uacac\ud574\ub97c \ubc1d\ud799\ub2c8\ub2e4.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/kymos.com\/ko\/news\/lluisa-garcia-%eb%b0%95%ec%82%ac%eb%8a%94-%ec%82%ac%eb%a5%b4%ed%83%84%ec%9d%98-n-%eb%8b%88%ed%8a%b8%eb%a1%9c%ec%82%ac%eb%af%bc-%eb%b6%88%ec%88%9c%eb%ac%bc%ec%9d%84-%ea%b4%80%eb%a6%ac%ed%95%98%eb%8a%94\/\" \/>\n<meta property=\"og:locale\" content=\"ko_KR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\ud1b5\ucc30\ub825\uc0ac\ub974\ud0c4\uc758 N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc \ubd88\uc21c\ubb3c\uc744 \uad00\ub9ac\ud558\ub294 \ubc29\ubc95\" \/>\n<meta property=\"og:description\" content=\"\uc0ac\ub974\ud0c4\uc73c\ub85c \uc54c\ub824\uc9c4 \ud608\uc555\uc57d\uc5d0\uc11c N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc \ubd88\uc21c\ubb3c\uc774 \ubc1c\uacac\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ub8e8\uc774\uc0ac \uac00\ub974\uc2dc\uc544 \ubc15\uc0ac\uac00 \uc790\uc2e0\uc758 \uacac\ud574\ub97c \ubc1d\ud799\ub2c8\ub2e4.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/kymos.com\/ko\/news\/lluisa-garcia-%eb%b0%95%ec%82%ac%eb%8a%94-%ec%82%ac%eb%a5%b4%ed%83%84%ec%9d%98-n-%eb%8b%88%ed%8a%b8%eb%a1%9c%ec%82%ac%eb%af%bc-%eb%b6%88%ec%88%9c%eb%ac%bc%ec%9d%84-%ea%b4%80%eb%a6%ac%ed%95%98%eb%8a%94\/\" \/>\n<meta property=\"og:site_name\" content=\"Kymos\" \/>\n<meta property=\"article:published_time\" content=\"2019-12-10T10:07:09+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/kymos.com\/wp-content\/uploads\/2019\/12\/Nitrosamines-interview-with-Lluisa_Short-e1658232221728.png\" \/>\n\t<meta property=\"og:image:width\" content=\"800\" \/>\n\t<meta property=\"og:image:height\" content=\"444\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Joan Puig de Dou\" \/>\n<meta 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\uc870\uc5b8\ud569\ub2c8\ub2e4.\",\"datePublished\":\"2019-12-10T10:07:09+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/kymos.com\\\/ko\\\/news\\\/lluisa-garcia-%eb%b0%95%ec%82%ac%eb%8a%94-%ec%82%ac%eb%a5%b4%ed%83%84%ec%9d%98-n-%eb%8b%88%ed%8a%b8%eb%a1%9c%ec%82%ac%eb%af%bc-%eb%b6%88%ec%88%9c%eb%ac%bc%ec%9d%84-%ea%b4%80%eb%a6%ac%ed%95%98%eb%8a%94\\\/\"},\"wordCount\":76,\"image\":{\"@id\":\"https:\\\/\\\/kymos.com\\\/ko\\\/news\\\/lluisa-garcia-%eb%b0%95%ec%82%ac%eb%8a%94-%ec%82%ac%eb%a5%b4%ed%83%84%ec%9d%98-n-%eb%8b%88%ed%8a%b8%eb%a1%9c%ec%82%ac%eb%af%bc-%eb%b6%88%ec%88%9c%eb%ac%bc%ec%9d%84-%ea%b4%80%eb%a6%ac%ed%95%98%eb%8a%94\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/kymos.com\\\/wp-content\\\/uploads\\\/2019\\\/12\\\/Nitrosamines-interview-with-Lluisa_Short-e1658232221728.png\",\"articleSection\":[\"\uc0dd\ubb3c\ubd84\uc11d\",\"\uc528\uc5e0\uc528\"],\"inLanguage\":\"ko-KR\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/kymos.com\\\/ko\\\/news\\\/lluisa-garcia-%eb%b0%95%ec%82%ac%eb%8a%94-%ec%82%ac%eb%a5%b4%ed%83%84%ec%9d%98-n-%eb%8b%88%ed%8a%b8%eb%a1%9c%ec%82%ac%eb%af%bc-%eb%b6%88%ec%88%9c%eb%ac%bc%ec%9d%84-%ea%b4%80%eb%a6%ac%ed%95%98%eb%8a%94\\\/\",\"url\":\"https:\\\/\\\/kymos.com\\\/ko\\\/news\\\/lluisa-garcia-%eb%b0%95%ec%82%ac%eb%8a%94-%ec%82%ac%eb%a5%b4%ed%83%84%ec%9d%98-n-%eb%8b%88%ed%8a%b8%eb%a1%9c%ec%82%ac%eb%af%bc-%eb%b6%88%ec%88%9c%eb%ac%bc%ec%9d%84-%ea%b4%80%eb%a6%ac%ed%95%98%eb%8a%94\\\/\",\"name\":\"\ud1b5\ucc30\ub825\uc0ac\ub974\ud0c4\uc758 N-\ub2c8\ud2b8\ub85c\uc0ac\ubbfc \ubd88\uc21c\ubb3c\uc744 \uad00\ub9ac\ud558\ub294 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